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Increasing Serum Sodium After Surgery for Tumor in the Pituitary Region 

Increasing Serum Sodium After Surgery for Tumor in the Pituitary Region
Chapter:
Increasing Serum Sodium After Surgery for Tumor in the Pituitary Region
Source:
Neurocritical Care (2 ed.)
Author(s):

Eelco F. M. Wijdicks

, Alejandro A. Rabinstein

, Sara E. Hocker

, and Jennifer E. Fugate

DOI:
10.1093/med/9780190602659.003.0035

Postoperative polyuria after surgery for a suprasellar tumor should promptly raise suspicion of diabetes insipidus. Diagnosis of diabetes insipidus is based on the presence of polyuria associated with hypernatremia, serum hyperosmolality, and urine hypoosmolality. Diabetes insipidus is a difficult management problem after surgery for resection of a centrally located brain tumor. In a catastrophically injured patient, diabetes insipidus may be one of the first signs of brain death. Fluid management, administration of vasopressin, and monitoring of effect of treatment are discussed in this chapter. Management of central diabetes insipidus consists of aggressive rehydration and intravenous administration of desmopressin.

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