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Neuromuscular Disorders 

Neuromuscular Disorders
Chapter:
Neuromuscular Disorders
Source:
Introduction to Clinical Neurology (5 ed.)
Author(s):

Mark B. Bromberg

and Douglas J. Gelb

DOI:
10.1093/med/9780190467197.003.0006

Unlike the central nervous system, where a single structural lesion may produce widespread effects because of disruption of ascending and descending fiber tracts, a single structural lesion in the peripheral nervous system produces symptoms in a narrowly localized region, often in a single limb. Many diseases affect the peripheral nervous system diffusely, however, and can’t be localized to a single lesion site. The autonomic, somatic sensory and somatic motor nerves are physically intermingled at some levels of the nervous system and separated at others, but it is useful to conceptualize them as distinct path- ways. Each can be associated with a variety of symptoms.

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