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Cognitive Enhancement in Epilepsy 

Cognitive Enhancement in Epilepsy
Cognitive Enhancement in Epilepsy
Cognitive Enhancement in CNS Disorders and Beyond

Beth A. Leeman-Markowski

and Kimford J. Meador


Cognitive deficits, including attention, language, and memory dysfunction, are common in the setting of epilepsy and can greatly impair quality of life. Cognitive dysfunction in epilepsy is often multifactorial and may relate to the underlying etiology or epilepsy syndrome, comorbid psychiatric disease, interictal epileptiform discharges, effects of seizures, antiepileptic drugs, and surgical interventions. Studies have addressed the prevention of impairment and, less commonly, methods for cognitive enhancement. This chapter examines the possible underlying mechanisms of cognitive deficits in epilepsy, methods for prevention of dysfunction, issues in study design, and data regarding cognitive enhancement.

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