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Targeted Treatment for Cognitive Impairment Associated with Cancer and Cancer Treatment 

Targeted Treatment for Cognitive Impairment Associated with Cancer and Cancer Treatment
Chapter:
Targeted Treatment for Cognitive Impairment Associated with Cancer and Cancer Treatment
Source:
Cognitive Enhancement in CNS Disorders and Beyond
Author(s):

Shelli R. Kesler

and Jeffrey S. Wefel

DOI:
10.1093/med/9780190214401.003.0013

Cognitive difficulty is one of the most common quality-of-life complaints among cancer patients and survivors. Cancer-related cognitive impairment (CRCI) is a common problem among cancer patients and survivors that extends disease-related morbidity; reduces quality of life; interferes with treatment adherence; and is a significant predictor of health behavior, disease progression, and survival. Several emerging management strategies for CRCI show promise for preventing and/or ameliorating CRCI. This chapter describes the incidence, symptoms, and putative mechanisms of CRCI and then discusses potential approaches for addressing CRCI. The focus of the interventions discussed in this chapter is on directions for future research that will potentially lead to widely accessible, effective, and ecologically valid approaches.

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