Page of

Growth Factors for Neurons Provided by Macroglial Cells 

Growth Factors for Neurons Provided by Macroglial Cells
Chapter:
Growth Factors for Neurons Provided by Macroglial Cells
Source:
Neuroglia (2 ed.)
Author(s):

Bernhard Reuss

and Klaus Unsicker

DOI:
10.1093/acprof:oso/9780195152227.003.0030

Neuronal survival and functions require bidirectional communication between neurons and glia that involves a large variety of growth factors. Neurotrophic factors are operationally defined as proteins that regulate neuron survival and differentiation. They can be synthesized by nonneuronal target cells, neurons, and glial cells. This chapter focuses on neurotrophic factors secreted from macroglial cells, that is, astrocytes, oligodendrocytes, and Schwann cells, and their effects on neuronal differentiation and survival in the intact and lesioned brain and peripheral nervous system.

Sign In

Copyright © 2020. All rights reserved.