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The Bedside Dysmorphologist is a thoughtful clinical guide to common--and often quite subtle--congenital malformations in clinical exam. Organized by area of the body, each section provides the user with a concise, illustrated roadmap for assessment and differential diagnosis of highly nuanced elements of dysmorphology. Narrated by a world-class clinical geneticist and enriched with a library of original photos, it provides a safety net for physicians encountering abnormalities in physical exam.Less

Providing both a clinical and scientific perspective on irritability in children, this new online resource is a timely look at recent developments in the field. Currently there is a lively scientific debate how irritability contributes to various psychopathological syndromes. The major classification systems are responding–DSM-5 has created a new diagnosis of disruptive mood dysregulation disorder and ICD-11 is considering how to include irritability as an entity. Abnormal states of anger are a common reason for referral to child health services, and cause concern in clinics, schools, and families. Misdiagnosis and treatment can stem from a lack of understanding of the mechanisms involved in high levels of anger in children, and this title provides clear guidance on the development of abnormal states of anger, their consequences for later development, and how to assess and make differential diagnoses between them. Less

Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is one of the most common single gene disorders found in the developed world. In this fourth edition of the classic monograph on the topic, Alan Emery and Francesco Muntoni are joined by Rosaline Quinlivan, Consultant in Neuromuscular Disorders, to provide a thorough update on all aspects of the disorder. Recent understanding of the nature of the genetic defect responsible for Duchenne Muscular Dystrophy and isolation of the protein dystrophin has led to the development of new theories for the disease's pathogenesis. This new edition incorporates these advances from the field of molecular biology, and describes the resultant opportunities for screening, prenatal diagnosis, genetic counselling and from recent pioneering work with anti-sense oligonucleotides, the possibility of effective RNA therapy. Although there is still no cure for the disorder, there have been significant developments concerning the gene basis, publication of standards of care guidelines, and improvements in management leading to significantly longer survival, particularly with cardio-pulmonary care. The authors also investigate other forms of pharmacological, cellular and gene therapies.Less

The second edition of this essential handbook provides a practical, accessible guide to all emergency situations encountered in paediatrics and neonatology, from the immediately life-threatening to the smaller but urgent problems that may arise.Less

Antimicrobial agents either kill (bactericidal) or inhibit (bacteriostatic) the growth of a microorganism by targeting specific unique bacterial sites or metabolic pathways. Common antibiotic adverse effects and toxicities include allergic reactions, numerous possible toxicities, alteration of human flora, drug interactions, and promoting of antibiotic resistance. Presumptive and empirical therapy relies on the clinical syndrome and anatomical site of infection. Factors to consider when choosing empirical therapy include identification of the organism, the estimated benefit to the patient, the probable susceptibility of the isolated (or suspected) pathogen based on laboratory results or local epidemiological parameters, and pharmacokinetic/pharmacodynamic considerations. Host factors, including age, immune deficiency status, and other underlying conditions, should always be considered when choosing an antibiotic. There are few absolute indications for the prophylactic use of antimicrobials, and this is one area where misuse is common. The susceptibility of common pathogens is often predictable, allowing adequate empirical treatment. The main driver for the development of antibiotic resistance is the inappropriate use of antibiotics. Bacteria may be naturally resistant or may acquire resistance by means of DNA mutation or acquisition of resistance-conferring DNA from another source (e.g. plasmids). Mechanisms of antibiotic resistance include chemical modification of antibiotics, reduced uptake into cells, active efflux from cells, target site modification, overproduction of antibiotic target, and metabolic bypass of inhibited reaction. Control of resistance may be achieved through adherence to prescribing guidelines, restriction policies that reduce the use of certain antibiotics, and antimicrobial stewardship programmes.Less

This book provides a question-and-answer review in an easy-to-read format. It was created to prepare the reader for the American Board of Psychiatry and Neurology (ABPN) certification and recertification examinations. It was specifically designed to cover the topics listed in the ABPN content outline, including basic neuroscience, behavioral neurology, psychiatry, and clinical neurology (adult and child). Cerebrovascular disease, epilepsy, neuromuscular diseases, movement disorders, demyelinating diseases, critical care, trauma, and neurologic complications of systemic disease are covered, as well as neuroanatomy, neuroinfectious diseases, neurologic complications of systemic diseases, substance abuse, sleep disorders, dementia, neurotoxicology, and neuropharmacology. The book also may used to prepare for the Residency In-Service Training Exam (RITE). The book includes questions about recent practice parameters published by the American Academy of Neurology. Multiple question formats were utilized, including case-based questions.Less

Now in its second edition, the Oxford Handbook of Neonatology is a user-friendly guide for all healthcare professionals involved in the care of newborns. Accessible, practical, and updated with the latest evidence, this new addition to the bestselling Oxford Medical Handbook series is a key resource designed for use at the cot-side. Using guidance from the Royal College of Paediatrics and Child Health and including the most up-to-date NICE guidelines, the second edition of this handbook uses diagrams and an easy-to-assimilate format to cover good communication practice, neonatal emergencies, and technical procedures. With a new chapter on endocrinology, and fully updated and expanded sections covering therapeutic hypothermia and developmental care, amongst other advances in the field, the Oxford Handbook of Neonatology addresses post-natal and antenatal care and commonly encountered problems. It includes specific sections on cardiology, neurology, and haematology alongside other key areas needed for the clinician working with newborns.Less

This invaluable reference covers all significant aspects of acute and chronic paediatrics. Areas such as neonatology, surgery, genetics and congenital malformations and child protection are covered in a user-friendly and succinct style.Less

The Oxford Textbook of Paediatric Pain brings together an international team of experts to provide an authoritative and comprehensive textbook on all aspects of pain in infants, children and youth. Divided into nine sections, this resource analyses pain as a multifactorial problem and gives the reader a comprehensive understanding of this challenging subject. Topics covered include the biological, social, and psychological basis of pain, pain in specific populations, pain measurement, pharmacology, psychosocial and physical interventions, complementary therapies, education, and ethics of pain control in youths, children, and infants. Evidence-based chapters look in depth at areas ranging from the long-term effects of the pain in children, to sociodemographic differences in paediatric pain management. Case examples and online materials including scales, worksheets, and videos are provided to aid learning and illustrate the application of knowledge.Less

Comprehensive in scope and definitive in authority, this second edition has been thoroughly updated to cover new practices, current epidemiological data and the evolving models that support the delivery of palliative medicine to children. it is is an essential resource for anyone who works with children worldwide. Less

Paediatric Anaesthesia is a comprehensive yet concise text covering everything from day surgery to complicated tertiary referral centre procedures. It provides concise and readily accessible information to trainee and expert alike. The book begins with the basic sciences and founding principles of anaesthetic management; containing simple tips on how to approach the perioperative care of children. Thereafter, each specialty is covered in a logical manner from preoperative assessment to post-operative care. Finally, the book covers paediatric medical emergencies, resuscitation and transfer of the child. This second edition has been uniformly updated and written by leading authorities from across the UK.Less

This pocket handbook of paediatric neurology provides practical advice on the clinical approach, and ‘at a glance’ overviews and aides-memoire, to common and rare disorders and clinical scenarios. Precise and compact, the book includes many helpful tables (on aetiologies and differential diagnoses) and figures (e.g. innervations, neuroradiological anatomy). The book is divided into seven chapters: (1) Clinical approach, (2) Neurodiagnostic tools (both giving practical guidance on an orderly approach to how and why to perform specialist tests and how to interpret the results, along with introductions to neurophysiology and neuroradiology), (3) Signs and symptoms (offering a distinctive clinically oriented systematic approach), (4) Specific conditions, (5) ‘Real-life’ examples of consultations with other services, (6) Emergencies, and (7) A comprehensive, practically orientated Pharmacopeia. The Handbook’s contributors are trainees who have recently got to grips with the subject, and senior colleagues whose long teaching and clinical experience bring a fresh and pragmatic approach to everyday clinical situations This equips general and neurodevelopmental paediatricians with the knowledge they need to meet the neurological needs of the young people they see; provides an ideal introduction and essential reference for trainees on short-term child neurology attachments or subspecialty trainees in neurology, neurodisability, and developmental paediatrics. An international perspective includes North American emphases. The new edition has an expanded neuroimaging section and an increased emphasis on genetic aspects of neurological disease.Less

Looking after children with life-limiting conditions can be very difficult for both parents and health-care professionals. This second edition of Paediatric Palliative Medicine is full of easily accessible, detailed information on medical conditions and symptoms, and includes specific management plans in order to guide the practising clinician through treatment of children requiring palliative care. Using the bestselling Oxford Specialist Handbook format to deliver practical and concise information, this handbook facilitates bedside delivery of effective palliative medicine. It includes detailed information on symptom control and the philosophy and models that support delivery of palliative medicine to children, while also covering practical delivery of palliative medicine relating to other professionals and families, and the learning and coping skills required in palliative care. It also contains a quick-reference drug formulary. Fully updated with an expanded formulary and a new chapter on the intensive care unit, this new edition continues to be the authoritative reference tool in paediatric palliative care.Less

This new edition covers all areas associated with treating acute or chronic respiratory problems in children. It discusses the approach to clinical problems, specific conditions, supportive care and practical procedures, and includes vital appendices covering specific tests and statistics. Designed as a practical guide, it serves general and specialist paediatricians at both consultant and trainee level. Divided into five parts, it provides a practical approach to acute and non-acute clinical problems;, detailed information about common and more rare clinical conditions, useful information on supportive care, including the use of non-invasive ventilation and the care of a child with a tracheotomy; and details on how to perform several practical procedures, such as ciliary brush biopsy, flexible bronchoscopy, and inserting a chest drain. The appendices provide information on lung function testing and tables of age-corrected normal values for several respiratory parameters.Less

Paediatric Rheumatology, second edition is an indispensable resource for the identification and management of rheumatological diseases of children and young people. As well as covering common and rare musculoskeletal problems, there are also chapters on rheumatological emergencies designed for quick reference, and essential core clinical skills of relevance to the full spectrum of paediatric rheumatological disease. This second edition is fully updated, including state-of-the-art descriptions of new autoinflammatory diseases, advances in genetics in paediatric rheumatology, up-to-date guidance on the treatment of JIA, vasculitis, SLE, JDM, and other connective tissue diseases. Highlights of the second edition include alignment of management approaches for paediatric rheumatological diseases with recent evidence-based / consensus European guidelines; a description of North American treatment approaches to JIA; updated chapters on more specialist interventions including immunization in the immunosuppressed, and haematopoietic stem cell transplantation; and sections describing approaches to the management of rheumatological diseases in developing countries. Bone diseases are also described in detail including CRMO, skeletal dysplasias, and metabolic bone diseases. The second edition also includes a colour plate depicting rashes presenting in paediatric rheumatological conditions. This second edition is fully endorsed by the British Society for Paediatric and Adolescent Rheumatology (BSPAR), and many members of BSPAR have contributed most of the chapters. This second edition thus provides fully updated clinical guidelines and supporting information needed to successfully manage children and young people with rheumatological conditions.Less

Pediatric Anesthesiology: A Comprehensive Board Review is a high-yield, streamlined study aid. It contains more than 800, realistic, multiple-choice questions tailored to the keywords in the outline of the Pediatric Anesthesiology Certification Examination published by the American Board of Anesthesiology (ABA). To maximize reading efficiency, annotated answers are followed by bulleted key facts and key references. With this book as guide, readers will be able to efficiently prepare for the written primary certification pediatric anesthesiology board exam. Less

Featuring 150 cases and over 400 high-quality images, this resource offers a complete survey of the field of pediatric radiology. Cases are formatted as questions and answers, allowing for self-assessment, complete with relevant radiologic findings, differential diagnoses, teaching points, further steps in management, and suggested further readings. It offers a comprehensive overview of the clinical issues of pediatric radiology: cardiovascular system, gastrointestinal system, genitourinary system, spine, neuroradiology, chest and airway, and musculoskeletal system.Less

50 Studies Every Pediatrician Should Know presents key studies that have shaped the practice of pediatrics. As with the other volumes in the 50 Studies Every Doctor Should Know series, the studies herein represent the cumulative “canon” that many physicians have created individually and together to better understand the evidence behind pediatrics. Selected using a rigorous methodology, which included discussions with many of the original authors or research team members, the studies cover topics including general pediatrics, behavioral pediatrics, infectious diseases, cardiology, neonatology, endocrinology, allergy/immunology, rheumatology, nephrology, hematology, dermatology, otolaryngology, and orthopedics, and represent the current controlling evidence in pediatrics. For each study, a concise summary in presented with an emphasis on the results and limitations of the study, as well as its implications for practice and brief information from other relevant studies. An illustrative clinical case concludes each review, allowing the reader to practice applying the findings to a clinical situation.Less

This resource codifies the knowledge base and offers an authoritative and comprehensive guide to the important new field of children's environmental health. Edited by two internationally recognized pioneers in the area, it presents up-to-date information on the chemical, biological, physical, and societal hazards that confront children in today's world: pesticides, indoor and outdoor air pollution, lead, arsenic, phthalates, bisphenol A, brominated flame retardants, ionizing radiation, electromagnetic fields, and the built environment. It presents carefully documented data on rising rates of disease in children, offers a critical summary of new research linking pediatric disease with environmental exposures, and explores the cellular, molecular, and epigenetic mechanisms underlying diseases of environmental origin. Less

Training in Paediatrics covers the broad knowledge-base required by postgraduate trainees choosing to specialise in paediatrics, from their intial Foundation Year placements through to examination for Membership of the Royal College of Paediatrics and Child Health (MRCPCH examinations). Less