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The definitive guide to clinical neurology, the twelfth edition of Brain's Diseases of the Nervous System provides detailed coverage of the full range of major neurological conditions, and includes updated sections on genetics, development neurology, and re-written introductory chapters.Less

This book represents the final work of the late Professor C. David Marsden, and serves as the 'clinical Bible' for the management of movement disorders. Extensively illustrated with many original photographs and diagrams of historical significance that have not been published previously, it is an essential reference not just for movement disorder specialists and researchers, but also for clinicians who care for patients with these disorders.Less

The New Oxford Textbook of Psychiatry is one of the leading reference works in this field. Bringing together over 200 chapters from the leading figures in the discipline, it presents a comprehensive account of clinical psychiatry, with reference to its scientific basis and to the patient's perspective throughout. Less

Heart failure is epidemic throughout the world. A growing incidence and prevalence has resulted in a large population of individuals transitioning to advanced stages of the syndrome and requiring uniquely specialized therapies and cardiac transplantation. The Oxford Textbook of Advanced Heart Failure and Cardiac Transplantation is a focused and comprehensive work covering this new and rapidly growing cardiovascular subspecialty. Authored by eminent international experts, it is the authoritative text on advanced heart failure and a central resource for clinicians caring for patients with this condition. Key areas of focus are the immunology and hemodynamic alterations characteristic of advanced stages of heart failure; device therapy including left and right ventricular assist devices; cardiac resynchronization therapy; implantable cardioverter defibrillators; and implantable monitoring devices. By covering a range of characteristics, therapeutic challenges, and practical aspects of managing patients this book provides an in-depth source for cardiologists and other related clinicians. A strong focus on the difficult decision-making needed to handle advanced heart failure cases, along with specific knowledge of epidemiology, biology, and pathophysiology, creates a key tool for optimally managing these complex patients.Less

This two-volume work of 91 chapters covers all aspects of practice in anaesthesia. Volume 1 addresses the underpinning sciences of anaesthesia including physiology, pharmacology, physics, anaesthetic equipment, statistics, and evidence-based anaesthesia. Volume 1 also outlines the fundamental principles of anaesthetic practice including ethics, risk, informatics and technology for anaesthesia, human factors and simulation in anaesthetic practice, safety and quality assurance in anaesthesia, teaching, research, and outcomes, as well as all stages of the perioperative journey including preoperative assessment and optimization for anaesthesia, intraoperative monitoring, avoiding and managing hazards, post-surgical analgesia and acute pain management, and post-surgical anaesthetic complications. Volume 2 focuses on the clinical aspects of anaesthesia, including procedures, techniques and therapies, regional anaesthesia, the conduct of anaesthesia by surgical specialty, and paediatric and neonatal anaesthesia, including the resuscitation, stabilization, and transfer of sick and injured children. The clinical second volume also addresses the conduct of anaesthesia outside the operating theatre, including pre-hospital care, anaesthesia in remote locations, and military anaesthesia. The core knowledge for providing anaesthesia and managing comorbidities is provided, and in addition, those aspects of intensive care and pain medicine that are core knowledge for the general anaesthetist are covered. The book brings together key concepts, pertinent research from ongoing scientific endeavours, and clinical practice guidelines.Less

An authoritative, evidence based textbook on oral, dental, and maxillofacial surgery: one of the most common indications for anaesthesia worldwide.

This resource provides a comprehensive and detailed overview of all aspects of anaesthesia for the elderly patient looking at the effect of ageing on the systems of the body and the role that age has on drug mechanisms. Designed for both consultants and trainees who care for elderly patients, chapters address the clinical management of the older patient in pain, trauma, intensive care as well as anaesthesia for all aspects of surgery. The expert author team use their experience to provide a practical and stimulating resource which informs everyday clinical activity and explores the unanswered questions which face anaesthetists in this changing patient population. Less

The Oxford Textbook of Attention Deficit Hyperactivity Disorder provides an authoritative, multidisciplinary text displaying the latest research developments in the diagnosis, assessment, and management of patients with ADHD. Organized into eight key sections, this textbook covers the aetiology, pathophysiology, epidemiology, clinical presentation, comorbidity, clinical assessment, and clinical management of ADHD. Individual chapters address key topics, such as the clinical assessment of ADHD in adults and different presentations of ADHD. They contain information on best practice, current diagnostic guidelines, including DSM-5 and ICD-11, and key up-to-date references for further reading.Less

Axial spondyloarthritis is a relatively new term, now becoming widely accepted in clinical practice, referring to inflammatory disease predominantly of the spine where the main symptom is back pain. The most common subset of AxSpA is ankylosing spondylitis. This is a rapidly evolving field with new diagnostic criteria and treatments, which are likely to evolve further. This book covers the significant recent advances in the epidemiology, genetics, pathogenesis, classification, and treatment of this disabling disease, from a truly global perspective.Less

The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside medical scientists. Oxford Textbook of Cancer Biology brings together the developments from different branches of research into one volume. Structured in seven sections, the book starts with a review of the development and biology of multicellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates how, once cells become neoplastic, their signalling network is altered and pathological behaviour follows. Changes that cancer cells can induce in nearby normal tissue are explored, and the new relationship established between them and the stroma is explicated. Finally, the authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology with its vast amounts of data are integrated with traditional cell biology to provide a global view of the disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving.Less