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This essential guide to the management of the acutely ill patient features expanded material on practical procedures and new information on common presentations.

This title covers the fundamentals of pain, the pharmacology of drugs used, and summarises the current evidence base for the management of acute pain.

Acute Pain Medicine tackles a large array of diagnostic and treatment consideration across a variety of surgical and nonsurgical acute pain conditions. It reviews a variety of acute pain–modulating factors followed by interventional and pharmacologic treatment options. For each applicable condition, perineural and neuraxial considerations are given when appropriate along with nociceptive anatomic complements. Pharmacologic modalities are described, stressing the use of multimodal analgesia and a variety of opioid-based options if necessary. The book reviews cases that commonly are associated with significant acute pain but also highlight the role of acute pain medicine physicians in the postdischarge phase. Finally, the book includes a critical update of the Military Advanced Regional Anesthesia and Analgesia handbook. This update serves as an essential bedside tool in the performance of regional anesthetic techniques and their corresponding anatomic considerations.Less

This resource is a concise companion for health care professionals who manage patients with acute lung infections.

Diagnosis and treatment of acute stroke has advanced considerably in the past 2 decades. Most notably, in cases of ischemic stroke, intravenous alteplase has become the standard of medical treatment despite its multiple contraindications and limited time window. More recently, trials have proven that endovascular thrombectomy is superior to medical therapy alone, advancing the standard of care for patients who present with acute ischemic stroke from a large vessel occlusion and salvageable brain tissue. The treatment of hemorrhagic stroke now involves the use of novel pharmacological agents and advanced minimally invasive technology. Important changes have also occurred at the levels of hospital organization and treatment decision-making. Such changes in organization and designation of hospitals with distinct levels of stroke care and the variety of stroke protocols now requires team work of emergency medical services (EMS), Emergency Department, stroke neurologists, neurosurgeons, and neurointerventionalists. This book provides an overview of the modern medical and surgical options for the treatment of patients with acute ischemic and hemorrhagic strokes. The pivotal role of EMS in prehospital evaluation and triage of a stroke patient and the levels of stroke systems of care are discussed. In addition, the current guidelines on the management of acute stroke, with the focus on early care of acute stroke patients at the Emergency Department and the first 24 hours of hospital admission, are reviewed. Each chapter contains a discussion of common clinical scenarios including initial management steps, practical points, and common pitfalls.Less

This thought-provoking resource presents an original philosophical analysis bringing together addiction and weakness of will. The author develops an integrated account of these two phenomena, rooted in a classical conception of akrasia as valuing without intending and at the same time intending without valuing. This fascinating and suggestive account addresses a number of paradoxes faced by current thinking about addiction and weakness of will, in particular the significance of control and intention for responsible action. Addiction and Weakness of Will makes an original contribution to central issues in moral psychology and philosophy of action, including the relationship between responsibility and intentional agency, and the nature and scope of moral appraisal. Less

Addictive disorders in older adults are underdiagnosed and undertreated. An important reason for this lack of recognition of a serious health problem is a paucity of clinical knowledge about how such disorders present in this population. The presentation for alcohol and substance use disorders in the elderly can be confusing, given the metabolic changes and concurrent conditions associated with aging, together with interactions between alcohol and prescribed psychoactive drugs. Further, screening instruments have not been validated for this population. Brief interventions may be effective but should take into account contextual needs such as medical conditions, cognitive decline, and mobility limitations. Treatment strategies, including detoxification regimens, need to be modified for older patients and - in the case of opioid dependence - must address the management of chronic pain in this population. Ironically, benzodiazepines are the most frequently prescribed psychoactive medication in the elderly, despite older individuals' greater sensitivity to side effects and toxicity. Older women are at particularly heightened vulnerability for iatrogenic dependence on sedatives and hypnotics. More clinical research data are needed to inform screening and referral strategies, behavioral therapies, and pharmacological treatment. At the same time, emerging technologies such as communication tools and monitoring devices offer important opportunities to advance addiction treatment and recovery management in older adults. Although research to date has been limited in this population, recent data suggest that treatment outcomes are equal or better to those seen in younger cohorts.Less

This online resource serves as a concise and practical guide to the management of ADHD and Hyperkinetic disorder. It provides a user-friendly introduction to the clinical understanding, evaluation, and treatment of ADHD. This edition has been updated to include new DSM-5 diagnostic criteria as of May 2013, and to reflect more published studies on ADHD in the adult population, along with new data on the CNS stimulant drug LDX (Lisdexamfetamine Dimesylate).Less

This resource is aimed at those interested in adult neurogenesis and stem cell biology of the adult brain, and covers the historical background and describes in detail adult neurogenesis in the hippocampus as well as the subventricular zone and olfactory bulb. It then discusses the regulatory mechanisms, and the subject of neurogenesis outside the "canonical" neurogenic regions of rodents and primates, as well as how adult neurogenesis in different species. It concludes with coverage of the provocative hypotheses that link failing adult neurogenesis with diseases such as temporal lobe epilepsy, major depression, schizophrenia, brain tumors, and dementias.Less

This book has grown out of decades of practicing simulation and teaching concepts of perioperative crisis resource management at our institutions, at national meetings, and in our residency and fellowship training programs. The purpose is to fill a gap between two areas of valuable work that exist in the perioperative emergency space; namely, between books that consist largely of steps of diagnosing a problem followed by a list of treatment steps and those reference books or articles that form the compendium works. As such, the goal of this volume is to be an up-to-date, high-yield, clinically relevant resource for understanding the epidemiology, pathophysiology, and proper assessment and management of a wide variety of perioperative emergencies. Our target audience is anesthesiologists, nurse anesthetists, surgeons, recovery and critical care nurses, and anyone else practicing within the perioperative arena.Less