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- Chapter 1 Opioid Medications: Old Wine in New BottlesTimothy Atkinson, John J. Coleman, and Jeffrey Fudin
- Chapter 2 Legal Regulation of Prescription Opioids and PrescribersKelly K. Dineen and Adam J. Ruggles
- Chapter 3 Monitoring Prescriptions, Third-Party Healthcare Payers, Prescription Benefit Managers, and Private-Sector Policy OptionsJohn J. Coleman
- Chapter 4 Whatever Happened to the Decade of Pain Control and Research?John J. Coleman
- Chapter 5 Evaluation and Treatment of the Chronic Pain Patient: Practice and ComplexityJohn F. Peppin, Pravardhan Birthi, Bill H. McCarberg, and Yvonne D’Arcy
- Chapter 6 An Overview of the Abuse Potential of Nonopioids: Sedatives, Hypnotics, and StimulantsChristopher M. Herndon and Kelly N. Gable
- Chapter 7 Psychiatry and Chronic Pain: An Associative ConnectionHani Raoul Khouzam
- Chapter 8 Managing Pain in Patients with a History of a Substance Use Disorder: Challenges and OpportunitiesMartin D. Cheatle
- Chapter 9 Opioid Prescribing in Stigmatized and Special PopulationsKelly K. Dineen
- Chapter 10 The Demise of Interdisciplinary Chronic Pain Management and Its Relationship to the Scourge of Prescription Opioid Diversion and AbuseMichael E. Schatman
- Chapter 11 Pain Management Assessment Beyond the Physician Encounter: Urine Drug Monitoring and Patient AgreementsAnand C. Thakur