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Contents
- Front Matter
- Section 1 What is osteoarthritis?
- Chapter 1 Introduction: what is osteoarthritis?Michael Doherty, Johannes Bijlsma, Nigel Arden, David J. Hunter and Nicola Dalbeth
- Chapter 2 Palaeopathology of osteoarthritisJuliet Rogers and Paul Dieppe
- Chapter 3 Morphological aspects of pathologyLaura A. Wyatt and Michael Doherty
- Section 2 Tissues
- Chapter 4 Cartilage (including meniscus)Peter M. van der Kraan and Esmeralda N. Blaney Davidson
- Chapter 5 Pathophysiology of periarticular bone changes in osteoarthritisSteven R. Goldring
- Chapter 6 Synovium and capsuleFloris P. J. G. Lafeber, Nick J. Besselink, and Simon C. Mastbergen
- Chapter 7 The innervation of the joint and its role in osteoarthritis painJason J. McDougall and Joel A. Vilensky
- Section 3 Epidemiology
- Chapter 8 EpidemiologyNigel Arden and Michael C. Nevitt
- Section 4 Risk factors
- Chapter 9 GeneticsAna M. Valdes
- Chapter 10 Age, gender, race/ethnicity, and socioeconomic status in osteoarthritis and its outcomesJoanne M. Jordan, Kelli D. Allen, and Leigh F. Callahan
- Chapter 11 MorphologyRichard Aspden and Jenny Gregory
- Chapter 12 LifestyleJos Runhaar and Sita M. A. Bierma-Zeinstra
- Section 5 Pain
- Section 6 Clinical assessment
- Chapter 15 Clinical assessment: signs, symptoms, and patient perceptions in osteoarthritisMargreet Kloppenburg
- Chapter 16 Radiography and computed tomography imaging of osteoarthritisDaichi Hayashi, Ali Guermazi, and Frank W. Roemer
- Chapter 17 Ultrasound in osteoarthritis and crystal-related arthropathiesWalter Grassi, Tadashi Okano, and Emilio Filippucci
- Chapter 18 Imaging: magnetic resonance imagingDavid J. Hunter, Frank W. Roemer, and Ed Riordan
- Chapter 19 Laboratory testsLeticia A. Deveza, Changhai Ding, Xingzhong Jin, Xia Wang, Zhaohua Zhu, and David J. Hunter
- Section 7 Management
- Chapter 20 Introduction: the comprehensive approachMichael Doherty, Johannes Bijlsma, Nigel Arden, David J. Hunter, and Nicola Dalbeth
- Chapter 21 Patient information strategies for decision-making and management of osteoarthritisGillian Hawker, Anne Lyddiatt, Linda Li, Dawn Stacey, Susan Jaglal, Sarah Munce, and Esther Waugh
- Chapter 22 Exercise for the person with osteoarthritisKim L. Bennell, Ans Van Ginckel, Fiona Dobson, and Rana S. Hinman
- Chapter 23 Weight lossMarius Henriksen, Robin Christensen, Berit L. Heitmann, and Henning Bliddal
- Chapter 24 Addressing adverse mechanical factorsChristelle Nguyen and François Rannou
- Chapter 25 Psychological strategies in osteoarthritis of the knee or hipJoost Dekker, Daniel Bossen, Jasmijn Holla, Mariëtte de Rooij, Cindy Veenhof, and Marike van der Leeden
- Chapter 26 Miscellaneous physical therapiesMelanie A. Holden, Martin J. Thomas, and Krysia S. Dziedzic
- Chapter 27 Placebo, nocebo, and contextual effectsAbhishek Abhishek and Michael Doherty
- Section 8 Pharmacological therapies
- Chapter 28 Topical pharmacological treatmentsAbhishek Abhishek, Adrian Jones, and Michael Doherty
- Chapter 29 Systemic analgesics (including paracetamol and opioids)Bernard Bannwarth and Francis Berenbaum
- Chapter 30 Non-steroidal anti-inflammatory drugsLee S. Simon and Marc C. Hochberg
- Chapter 31 Supplements for the treatment of osteoarthritisAllen D. Sawitzke and Daniel O. Clegg
- Chapter 32 Intra-articular injection therapyNigel Arden and Terence O’Neill
- Section 9 Surgery
- Chapter 33 Arthroplasty and its complicationsAndrew Price, Paul Monk, and David Beard
- Chapter 34 Other surgical approaches in the management of osteoarthritisJonas Bloch Thorlund and L. Stefan Lohmander
- Section 10 Prospects for disease modification
- Chapter 35 Prospects for disease modificationShirley P. Yu and David J. Hunter
- Section 11 Delivery of care
- Chapter 36 Delivery (organization and outcome)Caroline A. Brand and Ilana N. Ackerman
- Section 12 Guidelines
- Chapter 37 GuidelinesWeiya Zhang and Michael Doherty
- Section 13 Gout
- Chapter 38 Epidemiology of goutSamantha Hider and Edward Roddy
- Chapter 39 Pathophysiology of goutNicola Dalbeth
- Chapter 40 The genetic basis of goutTony R. Merriman
- Chapter 41 Clinical presentation of goutTim L. Jansen
- Chapter 42 Laboratory investigations in goutEliseo Pascual and Francisca Sivera
- Chapter 43 Imaging of goutRobert T. Keenan, Sneha Pai, and Naomi Schlesinger
- Chapter 44 Principles of gout managementPascal Richette
- Chapter 45 Treatment of acute goutPuja Khanna
- Chapter 46 Long-term management of goutFernando Perez-Ruiz, Irati Urionagüena, and Sandra P. Chinchilla
- Chapter 47 Asymptomatic hyperuricaemia: to treat or not to treat?Thomas Bardin
- Section 14 Calcium pyrophosphate crystal deposition
- Chapter 48 Epidemiology and risk factors for calcium pyrophosphate depositionAbhishek Abhishek and Michael Doherty
- Chapter 49 Pathophysiology of calcium pyrophosphate depositionAbhishek Abhishek and Michael Doherty
- Chapter 50 Clinical features of calcium pyrophosphate crystal depositionAbhishek Abhishek and Michael Doherty
- Chapter 51 Investigations of calcium pyrophosphate depositionAbhishek Abhishek and Michael Doherty
- Chapter 52 Treatment of calcium pyrophosphate depositionAbhishek Abhishek and Michael Doherty
- Section 15 Basic calcium phosphate crystal deposition
- Chapter 53 Basic calcium phosphate crystal depositionNicola Dalbeth
- End Matter