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Contents
- Front Matter
- Section 1 Assessment of the patient with renal diseaseEdited by
Christopher G. Winearls
- Chapter 1 Epidemiology of kidney disease Aminu Bello, Marcello Tonelli, and Kitty Jager
- Chapter 2 Clinical assessment of the patient with renal disease: overview Christopher G. Winearls
- Chapter 3 Presentations of renal disease Christopher G. Winearls
- Chapter 4 Kidney disease-focused history taking Christopher G. Winearls
- Chapter 5 Kidney disease-focused features on examination Christopher G. Winearls
- Chapter 6 Urinalysis Walter P. Mutter
- Chapter 7 Assessment of renal function Marijn Speeckaert and Joris Delanghe
- Chapter 8 Tubular function Marijn Speeckaert and Joris Delanghe
- Chapter 9 Renal radiology: overview Michael J. Weston
- Chapter 10 Ionizing radiation and radiation protection Jeannette Kathrin Kraft and Peter Howells
- Chapter 11 Plain radiography, excretion radiography, and contrast radiography Akira Kawashima and Andrew J. LeRoy
- Chapter 12 Intervention Steven Kennish
- Chapter 13 Ultrasound Toby Wells and Simon J. Freeman
- Chapter 14 Computed tomography Eugene Teoh and Michael J. Weston
- Chapter 15 Magnetic resonance imaging James F. Glockner, Robert P. Hartman, Kazuhiro Kitajima, and Akira Kawashima
- Chapter 16 Radioisotopes in diagnostic imaging in nephrology Ramya Dhandapani and Sobhan Vinjamuri
- Chapter 17 Immunological investigation of the patient with renal disease Jo H. M. Berden and Jack F. M. Wetzels
- Chapter 18 The renal biopsy Ian S. D. Roberts, Philip Mason, and Agnes B. Fogo
- Chapter 19 Clinical trials: why and how in nephrology Richard Haynes, Martin J. Landray, William G. Herrington, and Colin Baigent
- Section 2 The Patient with fluid, electrolyte, and renal tubular disordersEdited by
Robert Unwin
- Chapter 20 An overview of tubular function Matthew A. Bailey
- Chapter 21 Sodium transport and balance: a key role for the distal nephron Laurent Schild
- Chapter 22 Water homeostasis David Marples and Søren Nielsen
- Chapter 23 Potassium homeostasis Alain Doucet and Gilles Crambert
- Chapter 24 Renal acid–base homeostasis Carsten A. Wagner and Olivier Devuyst
- Chapter 25 Phosphate homeostasis Heini Murer, Jürg Biber, and Carsten A. Wagner
- Chapter 26 Calcium homeostasis Francesco Trepiccione and Giovambattista Capasso
- Chapter 27 Magnesium homeostasis Pascal Houillier
- Chapter 28 Approach to the patient with hyponatraemia Ewout J. Hoorn and Robert Zietse
- Chapter 29 Approach to the patient with hypernatraemia Robert Zietse and Ewout Hoorn
- Chapter 30 Approach to the patient with oedema Jean-Marie Krzesinski and Eric P. Cohen
- Chapter 31 Approach to the patient with salt-wasting tubulopathies Detlef Bockenhauer and Robert Kleta
- Chapter 32 Approach to the patient with polyuria Daniel G. Bichet
- Chapter 33 Clinical use of diuretics David H. Ellison and Arohan R. Subramanya
- Chapter 34 Approach to the patient with hypo-/hyperkalaemia Charles S. Wingo and I. David Weiner
- Chapter 35 Approach to the patient with metabolic acidosis or alkalosis Mitchell L. Halperin and Kamel S. Kamel
- Chapter 36 Approach to the patient with renal tubular acidosis Stephen B. Walsh
- Chapter 37 Approach to the patient with hypercalcaemia Dennis Joseph and Theresa A. Guise
- Chapter 38 Approach to the patient with hypocalcaemia Agnès Linglart and Anne-Sophie Lambert
- Chapter 39 Approach to the patient with hypo-/hyperphosphataemia Judith Blaine, Hector Giral, Sabina Jelen, and Moshe Levi
- Chapter 40 Approach to the patient with hypomagnesaemia Martin Konrad and Karl P. Schlingmann
- Chapter 41 Approach to the patient with renal Fanconi syndrome, glycosuria, or aminoaciduria Detlef Bockenhauer and Robert Kleta
- Section 3 The patient with glomerular diseaseEdited by
Neil Turner
- Chapter 42 The glomerulus and the concept of glomerulonephritis Alexander Woywodt and Diana Chiu
- Chapter 43 The renal glomerulus: the structural basis of ultrafiltration Marlies Elger and Wilhelm Kriz
- Chapter 44 Function of the normal glomerulus Jean-Claude Dussaule, Martin Flamant, and Christos Chatziantoniou
- Chapter 45 Mechanisms of glomerular injury: overview Neil Turner
- Chapter 46 The patient with haematuria John Neary and Neil Turner
- Chapter 47 Loin pain haematuria syndrome John Neary
- Chapter 48 Nutcracker syndrome and phenomenon John Neary and Neil Turner
- Chapter 49 Exercise-related pseudonephritis Neil Turner
- Chapter 50 Proteinuria Neil Turner and Stewart Cameron
- Chapter 51 Postural proteinuria (benign orthostatic proteinuria) Neil Turner
- Chapter 52 Nephrotic syndrome Premil Rajakrishna, Stewart Cameron, and Neil Turner
- Chapter 53 Pathophysiology of oedema in nephrotic syndrome Neil Turner and Premil Rajakrishna
- Chapter 54 Idiopathic nephrotic syndrome: overview Patrick Niaudet and Alain Meyrier
- Chapter 55 Minimal change disease: clinical features and diagnosis Patrick Niaudet and Alain Meyrier
- Chapter 56 Minimal change disease: treatment and outcome Patrick Niaudet and Alain Meyrier
- Chapter 57 Primary focal segmental glomerulosclerosis: clinical features and diagnosis Alain Meyrier and Patrick Niaudet
- Chapter 58 Primary focal segmental glomerulosclerosis: treatment and outcome Alain Meyrier and Patrick Niaudet
- Chapter 59 Pathogenesis of proteinuria in minimal change disease and focal segmental glomerulosclerosis Patrick Niaudet and Alain Meyrier
- Chapter 60 Membranous glomerulonephritis: overview Daniel C. Cattran and Heather N. Reich
- Chapter 61 Membranous glomerulonephritis: clinical features and diagnosis Daniel C. Cattran and Heather N. Reich
- Chapter 62 Membranous glomerulonephritis: treatment and outcome Daniel C. Cattran and Heather N. Reich
- Chapter 63 Secondary membranous glomerulonephritis Daniel C. Cattran and Heather N. Reich
- Chapter 64 Membranous glomerulonephritis: pathogenesis Daniel C. Cattran and Heather N. Reich
- Chapter 65 Immunoglobulin A nephropathy: overview Kar Neng Lai and Sydney C. W. Tang
- Chapter 66 Immunoglobulin A nephropathy: clinical features Kar Neng Lai and Sydney C. W. Tang
- Chapter 67 Immunoglobulin A nephropathy diagnosis Kar Neng Lai and Sydney C. W. Tang
- Chapter 68 Immunoglobulin A nephropathy: treatment and outcome Kar Neng Lai and Sydney C. W. Tang
- Chapter 69 Immunoglobulin A nephropathy: pathogenesis Kar Neng Lai and Sydney C. W. Tang
- Chapter 70 Crescentic (rapidly progressive) glomerulonephritis Neil Turner
- Chapter 71 Antiglomerular basement membrane disease: overview Zhao Cui, Neil Turner, and Ming-hui Zhao
- Chapter 72 Antiglomerular basement membrane disease: clinical features and diagnosis Zhao Cui, Neil Turner, and Ming-hui Zhao
- Chapter 73 Antiglomerular basement membrane disease: treatment and outcome Zhao Cui, Neil Turner, and Ming-hui Zhao
- Chapter 74 Antiglomerular basement membrane disease: pathogenesis Zhao Cui, Neil Turner, and Ming-hui Zhao
- Chapter 75 Alport post-transplant antiglomerular basement membrane disease Zhao Cui, Neil Turner, and Ming-hui Zhao
- Chapter 76 Post-infectious glomerulonephritis: overview Bernardo Rodriguez-Iturbe and Mark Haas
- Chapter 77 Post-streptococcal glomerulonephritis Bernardo Rodríguez-Iturbe and Mark Haas
- Chapter 78 Immunoglobulin A-dominant post-infectious glomerulonephritis Bernardo Rodriguez-Iturbe and Mark Haas
- Chapter 79 Glomerulonephritis associated with endocarditis, deep-seated infections, and shunt nephritis Bernardo Rodriguez-Iturbe and Mark Haas
- Chapter 80 Membranoproliferative glomerulonephritis and C3 glomerulopathy Daniel P. Gale and Terry Cook
- Chapter 81 Fibrillary and immunotactoid glomerulopathy Stephen M. Korbet, Melvin M. Schwartz, and Edmund J. Lewis
- Chapter 82 Drug-induced and toxic glomerulopathies Alexander Woywodt and Diana Chiu
- Section 4 The patient with interstitial diseaseEdited by
Adrian Covic
- Chapter 83 Acute tubulointerstitial nephritis: overview Richard Baker
- Chapter 84 Drug-induced acute tubulointerstitial nephritis Hassan Izzedine and Victor Gueutin
- Chapter 85 Other toxic acute tubulointerstitial nephritis Benjamin J. Freda and Gregory L. Braden
- Chapter 86 Chronic tubulointerstitial nephritis: overview Adalbert Schiller, Adrian Covic, and Liviu Segall
- Chapter 87 Drug-induced chronic tubulointerstitial nephritis Hassan Izzedine and Victor Gueutin
- Chapter 88 Heavy metal-induced tubulointerstitial nephritis Patrick C. D’Haese, Benjamin A. Vervaet, and Anja Verhulst
- Chapter 89 Aristolochic acid nephropathy caused by ingestion of herbal medicinal products M. Refik Gökmen and Graham M. Lord
- Chapter 90 Balkan endemic nephropathy Milan Radović and Adalbert Schiller
- Chapter 91 Radiation nephropathy Lisa M. Phipps, Titi Chen, and David C. H. Harris
- Chapter 92 Urate nephropathy Duk-Hee Kang and Mehmet Kanbay
- Chapter 93 Immune-mediated tubulointerstitial nephritis Liviu Segall and Adrian Covic
- Section 5 The patient with reduced renal functionEdited by
David J. Goldsmith
- Chapter 94 Chronic kidney disease: definition, classification, and approach to management Ashish Upadhyay, Lesley A. Inker, and Andrew S. Levey
- Chapter 95 Chronic kidney disease in the developed world Morgan E. Grams and Josef Coresh
- Chapter 96 Chronic kidney disease in developing countries Luxia Zhang and Haiyan Wang
- Chapter 97 Chronic kidney disease long-term outcomes: progression, death, cardiovascular disease, infections, and hospitalizations Aiza Waheed, Monica Beaulieu, Catherine Weber, Nadia Zalunardo, and Adeera Levin
- Chapter 98 Cardiovascular disease and chronic kidney disease: overview David J. Goldsmith
- Chapter 99 Recommendations for management of high renal risk chronic kidney disease Charles J. Ferro and Khai Ping Ng
- Chapter 100 Hypertension as a cause of chronic kidney disease: what is the evidence? Rajiv Agarwal and Panagiotis I. Georgianos
- Chapter 101 Diet and the progression of chronic kidney disease Juan Jesús Carrero, Hong Xu, and Bengt Lindholm
- Chapter 102 Lipid disorders of patients with chronic kidney disease Alan G. Jardine and Rajan K. Patel
- Chapter 103 Smoking in chronic kidney disease Stephan R. Orth
- Chapter 104 Analytical aspects of measurements and laboratory values in kidney disease Edmund J. Lamb and Finlay MacKenzie
- Chapter 105 Effect of lifestyle modifications on patients with chronic kidney disease Andrew D. Williams, Robert G. Fassett, Erin J. Howden, and Jeff S. Coombes
- Chapter 106 Malnutrition, obesity, and undernutrition in chronic kidney disease Navneet Kumar, Heather Henderson, Beverly D. Cameron, and Peter A. McCullough
- Chapter 107 Left ventricular hypertrophy in chronic kidney disease Carmine Zoccali, Davide Bolignano, and Francesca Mallamaci
- Chapter 108 Sudden cardiac death in chronic kidney disease Reza Hajhosseiny, Kaivan Khavandi, and David J. Goldsmith
- Chapter 109 Epidemiology of calcium, phosphate, and parathyroid hormone disturbances in chronic kidney disease Patrick Biggar, Hansjörg Rothe, and Markus Ketteler
- Chapter 110 The role of inflammation in chronic kidney disease Juan Jesús Carrero and Peter Stenvinkel
- Chapter 111 Vascular stiffness in chronic kidney disease: pathophysiology and implications Jonathan N. Townend and Charles J. Ferro
- Chapter 112 Oxidative stress and its implications in chronic kidney disease Nosratola D. Vaziri
- Chapter 113 Abnormal endothelial vasomotor and secretory function Thimoteus Speer and Danilo Fliser
- Chapter 114 Endothelins and their antagonists in chronic kidney disease Neeraj Dhaun and David J. Webb
- Chapter 115 Chronic kidney disease-mineral and bone disorder: overview Stuart M. Sprague and Menaka Sarav
- Chapter 116 Imaging for detection of vascular disease in chronic kidney disease patients Paolo Raggi and Luis D’Marco
- Chapter 117 Pathophysiology of chronic kidney disease-mineral and bone disorder Ezequiel Bellorin-Font, Thanh-Mai Vo, Alexandra Voinescu, Nadia Wasi Iqbal, and Kevin J. Martin
- Chapter 118 Management of chronic kidney disease-mineral and bone disorder Thanh-Mai Vo, Ezequiel Bellorin-Font, and Kevin J. Martin
- Chapter 119 Fibroblast growth factor 23, Klotho, and phosphorus metabolism in chronic kidney disease Orlando M. Gutiérrez
- Chapter 120 Vascular calcification Adrian Covic, Mugurel Apetrii, Luminita Voroneanu, and David J. Goldsmith
- Chapter 121 Fractures in patients with chronic kidney disease Alastair J. Hutchison and Michael L. Picton
- Chapter 122 Spectrum of bone pathologies in chronic kidney disease Stuart M. Sprague and James M. Pullman
- Chapter 123 Clinical aspects and overview of renal anaemia Iain C. Macdougall
- Chapter 124 Erythropoiesis-stimulating agents in chronic kidney disease Iain C. Macdougall
- Chapter 125 Iron metabolism in chronic kidney disease Jolanta Malyszko and Iain C. Macdougall
- Chapter 126 Iron management in renal anaemia Iain C. Macdougall
- Chapter 127 Pleiotropic effects of vitamin D Kaivan Khavandi, Halima Amer, Sarah Withers, and Behdad Afzali
- Chapter 128 Immunity Behdad Afzali and Claudia Kemper
- Chapter 130 Gastroenterology and renal medicine Rishi M. Goel, Kamal V. Patel, and Terry Wong
- Chapter 131 Cutaneous manifestations of end-stage renal disease Timur A. Galperin, Kieron S. Leslie, and Antonia J. Cronin
- Chapter 132 The patient with reduced renal function: endocrinology Tomas Thor Agustsson and Paul Carroll
- Chapter 133 Sexual dysfunction Tomas Thor Agustsson and Paul Carroll
- Chapter 134 Health-related quality of life and the patient with chronic kidney disease Fredric O. Finkelstein and Susan H. Finkelstein
- Chapter 135 Coagulopathies in chronic kidney disease Seema Shrivastava, Beverley J. Hunt, and Anthony Dorling
- Chapter 136 Mechanisms of progression of chronic kidney disease: overview Neil Turner
- Chapter 137 Proteinuria as a direct cause of progression Jeremy Hughes
- Chapter 138 Nephron numbers and hyperfiltration as drivers of progression Valerie A. Luyckx
- Chapter 139 Podocyte loss as a common pathway to chronic kidney disease Wilhelm Kriz
- Chapter 140 Disordered scarring and failure of repair Jeremy S. Duffield
- Chapter 141 Modality selection for renal replacement therapy Raj Thuraisingham and Cormac Breen
- Chapter 142 Patient education and involvement in pre-dialysis management Sue Cox and Nicola Thomas
- Chapter 143 Preparation for renal replacement therapy Muh Geot Wong, Bruce A. Cooper, and Carol A. Pollock
- Chapter 144 Choices and considerations for in-centre versus home-based renal replacement therapy Karthik K. Tennankore and Christopher T. Chan
- Chapter 145 Conservative care in advanced chronic kidney disease Aine Burns and Fliss E. M. Murtagh
- Chapter 146 Palliative care in end-stage renal disease Katie Vinen, Fliss E. M. Murtagh, and Irene J. Higginson
- Chapter 147 Patient selection when resources are limited Bernadette A. Thomas and Christopher R. Blagg
- Chapter 148 Acidosis in chronic kidney disease Muhammad M. Yaqoob
- Section 6 The patient with another primary diagnosisEdited by
Giuseppe Remuzzi
- Chapter 149 The patient with diabetes mellitus Luigi Gnudi, Giorgio Gentile, and Piero Ruggenenti
- Chapter 150 Kidney involvement in plasma cell dyscrasias Pierre M. Ronco and Norbert Lameire
- Chapter 151 The patient with cryoglobulinaemia Fabrizio Fabrizi and Patrice Cacoub
- Chapter 152 The patient with amyloidosis Helen J. Lachmann and Giampaolo Merlini
- Chapter 153 The patient with myeloma Efstathios Kastritis and Meletios A. Dimopoulos
- Chapter 154 Light-chain deposition disease Dirk R. J. Kuypers and Morie A. Gertz
- Chapter 155 Other consequences from monoclonal immunoglobulins/fragments: Membranoproliferative glomerulonephritis and acquired Fanconi syndrome Fernando C. Fervenza, S. Vincent Rajkumar, An S. De Vriese, and Sanjeev Sethi
- Chapter 156 The patient with sarcoidosis Ravindra Rajakariar and Muhammad M. Yaqoob
- Chapter 157 The patient with vasculitis: overview David Jayne
- Chapter 158 The patient with vasculitis: pathogenesis Peter Heeringa and Coen A. Stegeman
- Chapter 159 The patient with vasculitis: clinical aspects Alan D. Salama
- Chapter 160 The patient with vasculitis: treatment and outcome Lorraine Harper and David Jayne
- Chapter 161 The patient with systemic lupus erythematosus: overview and pathogenesis Johan van der Vlag and Jo H. M. Berden
- Chapter 162 The patient with systemic lupus erythematosus: clinical features, investigations, and diagnosis Marie Condon, Philippa Dodd, and Liz Lightstone
- Chapter 163 The patient with systemic lupus erythematosus: treatment and outcome Frédéric A. Houssiau
- Chapter 164 The patient with antiphospholipid syndrome with or without lupus Bassam Alchi and David Jayne
- Chapter 165 The patient with scleroderma: systemic sclerosis Bernadette Lynch and Aine Burns
- Chapter 166 The patient with rheumatoid arthritis, mixed connective tissue disease, Sjögren syndrome, or polymyositis Lesley-Anne Bissell, Dwomoa Adu, and Paul Emery
- Chapter 167 The patient with sickle cell anaemia Jean-Philippe Haymann and Francois Lionnet
- Chapter 168 The obese patient (metabolic syndrome) Maarit Korkeila, Bengt Lindholm, and Peter Stenvinkel
- Chapter 169 The patient with hepatorenal syndrome Andrés Cárdenas and Pere Ginès
- Chapter 170 Kidney/ear syndromes Paul Goodyer
- Chapter 171 Kidney/eye syndromes Anna Paola Salvetti, Friederike Mackensen, Vedat Schwenger, and Heiko Billing
- Chapter 172 The patient with renal cell cancer Tim Eisen
- Chapter 173 The patient with Wilms tumour Eve Miller-Hodges and Christopher Mitchell
- Chapter 174 The patient with haemolytic uraemic syndrome/thrombotic thrombocytopenic purpura Marina Noris and Tim Goodship
- Section 7 The patient with urinary tract infectionEdited by
Neil Sheerin
- Chapter 175 Urinary tract infection in the adult: overview Neil Sheerin
- Chapter 176 Infection of the lower urinary tract Ased Ali and Rob Pickard
- Chapter 177 Upper urinary tract infection Mark Harber
- Chapter 178 Complicated urinary tract infection Ased Ali and Rob Pickard
- Chapter 179 Urinary tract infection in a patient with a kidney transplant Mark Harber
- Chapter 180 Urinary tract infection in infancy and childhood Heather Lambert
- Chapter 181 Schistosomiasis: the parasite and the host Rashad S. Barsoum
- Chapter 182 Schistosomiasis: clinical impact Rashad S. Barsoum
- Section 8 The patient with infections causing renal diseaseEdited by
Vivekanand Jha
- Chapter 183 Malaria Vinay Sakhuja and Harbir Singh Kohli
- Chapter 184 Leishmaniasis and trypanosomiasis Vinay Sakhuja and Harbir Singh Kohli
- Chapter 185 Hepatitis B Marion Muche and Seema Baid-Agrawal
- Chapter 186 Hepatitis C Fabrizio Fabrizi
- Chapter 187 HIV and renal disease Saraladevi Naicker and Graham Paget
- Chapter 188 Hantaviral infections Jan Clement, and Piet Maes
- Chapter 189 Dengue and other viral haemorrhagic fevers Jung-San Chang and Hung-Chun Chen
- Chapter 190 Yellow fever, severe acute respiratory syndrome virus, and H1N1 influenza infections Norbert Lameire
- Chapter 191 Leptospirosis Emmanuel A. Burdmann
- Chapter 192 Syphilis Emmanuel A. Burdmann
- Chapter 193 Rickettsiosis Emmanuel A. Burdmann and Vivekanad Jha
- Chapter 194 Schistosomiasis Rashad S. Barsoum
- Chapter 195 Nematode infections Raja Ramachandran and Vivekanand Jha
- Chapter 196 Mycobacterial infections: tuberculosis John Eastwood, Cathy Corbishley, John Grange, and Vivekanad Jha
- Chapter 197 Mycobacterial infections: leprosy and environmental mycobacteria John Eastwood, Cathy Corbishley, and John Grange
- Chapter 198 Renal involvement in other infections: diarrhoeal diseases, salmonella, melioidosis, and pregnancy Raja Ramachandran and Vivekanand Jha
- Section 9 The patient with urinary stone diseaseEdited by
Marc E. De Broe
- Chapter 199 Epidemiology of nephrolithiasis Eric N. Taylor and Gary C. Curhan
- Chapter 200 Approach to the patient with kidney stones Bhavna Chopra and Stanley Goldfarb
- Chapter 201 Calcium stones David A. Bushinsky and Orson Moe
- Chapter 202 Uric acid stones Michel Daudon and Paul Jungers
- Chapter 203 Cystine stones Michel Daudon and Paul Jungers
- Chapter 204 Cell biology of nephrocalcinosis/nephrolithiasis Benjamin A. Vervaet and Marc E. De Broe
- Chapter 205 Medical management of nephrocalcinosis and nephrolithiasis Bridget Sinnott, Naim M. Maalouf, Khashayar Sakhaee, and Orson W. Moe
- Chapter 206 Imaging and interventional treatment: urolithiasis from the surgeon’s point of view Gauthier Raynal and Olivier Traxer
- Section 10 The Patient with HypertensionEdited by
Neil Turner
- Chapter 207 The structure and function of renal blood vessels Karlhans Endlich and Rodger Loutzenhiser
- Chapter 208 Regulation of vasomotor tone in the afferent and efferent arterioles Karlhans Endlich and Rodger Loutzenhiser
- Chapter 209 Tubuloglomerular feedback, renal autoregulation, and renal protection Karlhans Endlich and Rodger Loutzenhiser
- Chapter 210 The kidney and control of blood pressure Olga Gonzalez-Albarrán and Luis M. Ruilope
- Chapter 211 The effect of hypertension on renal vasculature and structure Ulrich Wenzel, Thorsten Wiech, and Udo Helmchen
- Chapter 212 Ischaemic nephropathy Helen Alderson, Constantina Chrysochou, James Ritchie, and Philip A. Kalra
- Chapter 213 Renal artery stenosis: clinical features and diagnosis James Ritchie, Darren Green, Constantina Chrysochou, and Philip A. Kalra
- Chapter 214 Renal artery stenosis: diagnosis James Ritchie, Darren Green, Constantina Chrysochou, and Philip A. Kalra
- Chapter 215 Renal artery stenosis: management and outcome James Ritchie, Darren Green, Constantina Chrysochou, and Philip A. Kalra
- Chapter 216 Malignant hypertension Caroline Whitworth and Stewart Fleming
- Chapter 217 Resistant hypertension Iain M. MacIntyre and David J. Webb
- Chapter 218 The hypertensive child Wolfgang Rascher
- Chapter 219 Treatment of hypertension in children Wolfgang Rascher
- Section 11 The patient with acute kidney injury (and critical care nephrology)Edited by
Norbert Lameire
- Chapter 220 Definitions, classification, epidemiology, and risk factors of acute kidney injury Eric A. J. Hoste, John A. Kellum, and Norbert Lameire
- Chapter 221 Pathophysiology of acute kidney injury Michael S. Goligorsky and Julien Maizel (with contributions by Radovan Vasko, May M. Rabadi, and Brian B. Ratliff)
- Chapter 222 Clinical approach to the patient with acute kidney injury: diagnosis and differential diagnosis Norbert Lameire, Raymond Vanholder, and Wim Van Biesen
- Chapter 223 The role of novel biomarkers in acute kidney injury Norbert Lameire
- Chapter 224 Prevention of acute kidney injury: evaluation of important risk factors of acute kidney injury Norbert Lameire and Jill Vanmassenhove
- Chapter 225 Prevention of acute kidney injury: non-pharmacological strategies Norbert Lameire, Jill Vanmassenhove
- Chapter 226 Prevention of acute kidney injury: pharmacological strategies Norbert Lameire, Jill Vanmassenhove
- Chapter 227 Prevention of acute kidney injury: drug- and nephrotoxin-induced acute kidney injury Norbert Lameire
- Chapter 228 Non-dialytic management of the patient with acute kidney injury Achim Jörres, Dietrich Hasper, and Michael Oppert
- Chapter 229 Fluid overload in acute kidney injury Achim Jörres, Dietrich Hasper, and Michael Oppert
- Chapter 230 Electrolyte and acid–base disorders in AKI Achim Jörres, Dietrich Hasper, and Michael Oppert
- Chapter 231 Coagulation disturbances in acute kidney injury Achim Jörres, Dietrich Hasper, and Michael Oppert
- Chapter 232 Renal replacement therapy in the patient with acute kidney injury: overview Jang Won Seo and Ravindra L. Mehta
- Chapter 233 Intermittent acute renal replacement therapy Mark R. Marshall
- Chapter 234 Continuous renal replacement therapy Miet Schetz and Andrew Davenport
- Chapter 235 Peritoneal dialysis in acute kidney injury Wim Van Biesen
- Chapter 236 Scoring systems in acute kidney injury patients Angel Candela-Toha, Teresa Tenorio, Aurora Lietor, and Fernando Liaño
- Chapter 237 Overall outcomes of acute kidney injury Norbert Lameire, Wim Van Biesen, and Raymond Vanholder
- Chapter 238 Renal outcomes of acute kidney injury Norbert Lameire
- Chapter 239 Acute kidney injury in children Alexander Fichtner and Franz Schaefer
- Chapter 240 Acute kidney injury in the elderly Dinna N. Cruz, Anna Clementi, and Mitchell H. Rosner
- Chapter 241 Acute kidney injury in the tropics Vivekanand Jha
- Chapter 242 Acute kidney injury and hantavirus disease Jan Clement
- Chapter 243 Community-acquired pneumonia and acute kidney injury Norbert Lameire
- Chapter 244 Acute kidney injury in severe sepsis John Prowle and Rinaldo Bellomo
- Chapter 245 Cardiovascular surgery and acute kidney injury Jeremiah R. Brown and Chirag R. Parikh
- Chapter 246 Contrast-induced acute kidney injury Douglas Stewart, Gaurav Shah, Jeremiah R. Brown, and Peter A. McCullough
- Chapter 247 Renal failure in cirrhosis: pathogenesis, diagnosis, and treatment Vicente Arroyo, Mónica Guevara, and Javier Fernández
- Chapter 248 Acute kidney injury in heart failure Dinna N. Cruz, Anna Giuliani, and Claudio Ronco
- Chapter 249 Acute kidney injury in pulmonary diseases Soo Young Yoon and Ravindra L. Mehta
- Chapter 250 Acute kidney injury in pregnancy Duska Dragun and Björn Hegner
- Chapter 251 Acute kidney injury in the cancer patient Gilbert W. Moeckel, Veena Manjunath, and Mark A. Perazella
- Chapter 252 Acute kidney injury in polytrauma and rhabdomyolysis Mehmet Şükrü Sever and Raymond Vanholder
- Chapter 253 Acute kidney injury in patients with severe burn injury Nele Brusselaers and Eric A. J. Hoste
- Section 12 The patient on dialysisEdited by
Jonathan Himmelfarb
- Chapter 254 Overview of uraemic toxinsGriet Glorieux, Nathalie Neirynck, Anneleen Pletinck, Eva Schepers, and Raymond Vanholder
- Chapter 255 Haemodialysis: overview Jonathan Himmelfarb
- Chapter 256 Haemodialysis: vascular access Michael Allon
- Chapter 257 Haemodialysis: principles Claudio Ronco and William R. Clark
- Chapter 258 Haemodialysis: prescription and assessment of adequacy Scott D. Bieber and Jonathan Himmelfarb
- Chapter 259 Haemodialysis: acute complications Victor F. Seabra and Bertrand L. Jaber
- Chapter 260 Haemofiltration and haemodiafiltration Francesco Locatelli, Celestina Manzoni, Giuseppe Pontoriero, Vincenzo La Milia, and Salvatore Di Filippo
- Chapter 261 Dialysis withdrawal and palliative care Arkadiy Pinkhasov, Michael J. Germain, and Lewis M. Cohen
- Chapter 262 Frequent haemodialysis Alan S. Kliger and Rita Suri
- Chapter 263 Peritoneal dialysis: overview Rajnish Mehrotra and Jonathan Himmelfarb
- Chapter 264 Peritoneal dialysis: principles and peritoneal physiology Joanna Stachowska-Pietka, Jacek Waniewski, and Bengt Lindholm
- Chapter 265 Peritoneal dialysis: adequacy and prescription management Anjali Bhatt Saxena
- Chapter 266 Peritoneal dialysis: non-infectious complications Sara Dunsmore and Joanne M. Bargman
- Chapter 267 Overview of dialysis patient management and future directions Allen R. Nissenson, John Moran, and Robert Provenzano
- Chapter 268 Cardiovascular complications in end-stage renal disease patients: pathophysiological aspects Gerard M. London
- Chapter 269 Bacterial and fungal infections in patients on haemodialysis Laura Labriola, Eric Goffin, and Michel Jadoul
- Chapter 270 Bacterial and fungal infections in patients on peritoneal dialysis Eric Goffin, Laura Labriola, and Michel Jadoul
- Chapter 271 Viral infections in patients on dialysis Michel Jadoul, Laura Labriola, and Eric Goffin
- Chapter 272 Cognitive function, depression, and psychosocial adaptation Manjula Kurella Tamura, Mark L. Unruh, and Ea Wha Kang
- Chapter 273 Volume assessment and management in dialysis Rajiv Agarwal
- Chapter 274 Nutritional screening and nutritional management in dialysis patients Carla Maria Avesani, Juan Jesús Carrero, Bengt Lindholm, and Peter Stenvinkel
- Section 13 The transplant patientEdited by
Jeremy R. Chapman
- Chapter 275 The evolution of kidney transplantation Peter J. Morris and Jeremy R. Chapman
- Chapter 276 Pre-transplant assessment of the recipient Christophe Legendre
- Chapter 277 Organ donation Thomas Mone
- Chapter 278 Donor and recipient kidney transplantation surgery Richard D. M. Allen and Henry C. C. Pleass
- Chapter 279 Immunology, sensitization, and histocompatibility Thangamani Muthukumar, Darshana Dadhania, Choli Hartono, and Manikkam Suthanthiran
- Chapter 280 Immediate post-transplant care and surgical complications Simon R. Knight and Rutger J. Ploeg
- Chapter 281 Immunosuppression: drugs and protocolsDirk R. J. Kuypers and Maarten Naesens
- Chapter 282 Renal transplant imaging Simon Gruenewald and Philip Vladica
- Chapter 283 Rejection David N. Rush and Peter W. Nickerson
- Chapter 284 Infection: prophylaxis, diagnosis, and management Camille Nelson Kotton
- Chapter 285 Cardiovascular disease: prophylaxis, diagnosis, and management Emily P. McQuarrie, Hallvard Holdaas, Bengt Fellström, and Alan G. Jardine
- Chapter 286 Chronic allograft dysfunction Lorna K. Henderson, Brian J. Nankivell, and Jeremy R. Chapman
- Chapter 287 Cancer after kidney transplantation Germaine Wong and Angela C. Webster
- Chapter 288 Metabolic bone disease after renal transplantation Grahame J. Elder
- Chapter 289 Recurrent renal disease: prophylaxis, diagnosis, and management Philip Clayton and Steven Chadban
- Chapter 290 Paediatric renal transplantation Minnie M. Sarwal and Ron Shapiro
- Section 14 Renal disease at different stages of life (infancy, adolescence, pregnancy, old age)Edited by
Norbert Lameire and Neil Turner
- Chapter 291 Growth and development Lesley Rees
- Chapter 292 The adolescent with renal disease: transition to adult services Stephen D. Marks
- Chapter 293 Contraception in patients with kidney disease Kate Wiles and Catherine Nelson-Piercy
- Chapter 294 Pregnancy and renal physiologyKate Bramham and Catherine Nelson-Piercy
- Chapter 295 Pregnancy in patients with chronic kidney disease and on dialysis Kate Bramham, Priscilla Smith, and Catherine Nelson-Piercy
- Chapter 296 Pre-eclampsia and related disorders Kate Wiles and Catherine Nelson-Piercy
- Chapter 297 Acute kidney injury in pregnancy Kate Wiles and Catherine Nelson-Piercy
- Chapter 298 Specific renal conditions in pregnancy Kate Bramham, Priscilla Smith, and Catherine Nelson-Piercy
- Chapter 299 Pregnancy after renal transplantation Kate Bramham, Priscilla Smith, and Catherine Nelson-Piercy
- Chapter 300 The kidney in ageing: biology, anatomy, physiology, and clinical relevance Richard J. Glassock and Andrew D. Rule
- Section 15 The patient with genetic renal diseaseEdited by
Neil Turner
- Chapter 301 Ethical aspects of genetic testing Frances Flinter
- Chapter 302 Antenatal diagnosis and pre-implantation genetic testing Frances Flinter
- Chapter 303 The molecular basis of ciliopathies and cyst formation Wolfgang Kühn and Gerd Walz
- Chapter 304 The adult with renal cysts Yves Pirson and Olivier Devuyst
- Chapter 305 The child with renal cysts Carsten Bergmann, Nadina Ortiz-Brüchle, Valeska Frank, and Klaus Zerres
- Chapter 306 Autosomal dominant polycystic kidney disease: overview Albert C. M. Ong and Richard Sandford
- Chapter 307 Autosomal dominant polycystic kidney disease: clinical features Albert C. M. Ong and Timothy Ellam
- Chapter 308 Autosomal dominant polycystic kidney disease: diagnosis Richard Sandford
- Chapter 309 Autosomal dominant polycystic kidney disease management Young-Hwan Hwang and York Pei
- Chapter 310 Management of intracranial aneurysms Yves Pirson and Dominique Chauveau
- Chapter 311 Management of cystic liver disease René M. M. van Aerts, Tom J. G. Gevers and Joost P. H. Drenth
- Chapter 312 Autosomal dominant polycystic kidney disease in children and young adults Carsten Bergmann and Klaus Zerres
- Chapter 313 Autosomal recessive polycystic kidney disease Carsten Bergmann and Klaus Zerres
- Chapter 314 Bardet–Biedl syndrome and other ciliopathies Lukas Foggensteiner and Philip Beales
- Chapter 315 Hepatocyte nuclear factor-1B Coralie Bingham
- Chapter 316 Nephronophthisis and medullary cystic kidney disease: overview John A. Sayer
- Chapter 317 Nephronophthisis John A. Sayer and Roslyn J. Simms
- Chapter 318 Autosomal dominant tubule-interstitial kidney disease, including medullary cystic disease John A. Sayer
- Chapter 319 Oral-facial-digital type 1 syndrome Brunella Franco
- Chapter 320 The molecular basis of glomerular basement membrane disorders Rachel Lennon and Neil Turner
- Chapter 321 Alport syndrome: overview Laurence Heidet, Bertrand Knebelmann, and Marie Claire Gubler
- Chapter 322 Alport syndrome: clinical features Laurence Heidet, Bertrand Knebelmann, and Marie Claire Gubler
- Chapter 323 Alport syndrome: diagnosis Laurence Heidet, Bertrand Knebelmann, and Marie Claire Gubler
- Chapter 324 Alport syndrome: management Laurence Heidet, Bertrand Knebelmann, and Marie Claire Gubler
- Chapter 325 Thin glomerular basement membrane nephropathy and other collagenopathies Laurence Heidet, Bertrand Knebelmann, and Marie Claire Gubler
- Chapter 326 Nail patella syndrome Laurence Heidet and Marie Claire Gubler
- Chapter 327 Molecular basis of nephrotic syndrome Moin A. Saleem and Corinne Antignac
- Chapter 328 Molecular basis of renal tumour syndromes Thomas Connor and Patrick H. Maxwell
- Chapter 329 WT1 and its disorders Nick Hastie and Eve Miller-Hodges
- Chapter 330 Tuberous sclerosis complex renal disease Bradley P. Dixon, J. Christopher Kingswood, and John J. Bissler
- Chapter 331 Hypoxia-inducible factor and renal disorders Thomas Connor and Patrick H. Maxwell
- Chapter 332 Von Hippel–Lindau disease Thomas Connor and Patrick H. Maxwell
- Chapter 333 Molecular basis of complement-mediated renal disease Nicholas Medjeral-Thomas, Anna Richards, and Matthew C. Pickering
- Chapter 334 Inherited metabolic diseases and the kidney Robin Lachmann and Elaine Murphy
- Chapter 335 Fabry disease: overview and pathophysiology Stephen Waldek
- Chapter 336 Fabry disease: clinical features Stephen Waldek
- Chapter 337 Fabry disease: diagnosis Stephen Waldek
- Chapter 338 Fabry disease: management and outcome Stephen Waldek
- Chapter 339 Cystinosis Elena N. Levtchenko and Mirian C. Janssen
- Chapter 340 Mitochondrial diseases and the kidney Andrew Hall and Shamima Rahman
- Chapter 341 APOL1 and renal disease Neil Turner, Teena Tandon, and Rajiv Agarwal
- Chapter 342 MYH9 and renal disease Neil Turner and Bertrand Knebelmann
- Section 16 The patient with structural and congenital abnormalitiesEdited by
Adrian Woolf
- Chapter 343 Human kidney development Paul Winyard
- Chapter 344 Kidney stem cells Oren Pleniceanu and Benjamin Dekel
- Chapter 345 Anatomical types of congenital anomalies: overview of obstruction Michiel F. Schreuder
- Chapter 346 Renal agenesis Michiel F. Schreuder
- Chapter 347 Renal dysplasia Michiel F. Schreuder
- Chapter 348 Renal hypoplasia Michiel F. Schreuder
- Chapter 349 Normal variation in nephron numbers Michiel F. Schreuder
- Chapter 350 Renal tubular dysgenesis Michiel F. Schreuder
- Chapter 351 Congenital solitary functioning kidney Michiel F. Schreuder
- Chapter 352 Duplex, ectopic, and horseshoe kidneys Michiel F. Schreuder
- Chapter 353 Pelviureteric junction obstruction and megaureter in children Michiel F. Schreuder
- Chapter 354 Posterior urethral valves Michiel F. Schreuder
- Chapter 355 Primary vesicoureteric reflux and reflux nephropathy Heather Lambert
- Chapter 356 The patient with urinary tract obstruction Muhammad M. Yaqoob, Katherine Bennett-Richards, and Islam Junaid
- Chapter 357 Retroperitoneal fibrosis Muhammad M. Yaqoob, Katherine Bennett-Richards, and Islam Junaid
- Chapter 358 Branchio-oto-renal syndrome Udo Vester and Stefanie Weber
- Chapter 359 Townes–Brocks syndrome Udo Vester and Stefanie Weber
- Chapter 360 Renal coloboma syndrome Udo Vester and Stefanie Weber
- Chapter 361 Ante- and postnatal imaging to diagnose human kidney malformations Fred E. Avni, Marie Cassart, Anne Massez, and Michèle Hall
- Section 17 Drugs and renal diseaseEdited by
William G. Bennett
- Chapter 362 Drug-induced nephropathies Anushree Shirali and Mark A. Perazella
- Chapter 363 Drug dosing in chronic kidney disease Ali J. Olyaei, Ted A. Foster, and Edgar V. Lerma
- Chapter 364 Drug dosing in acute kidney injury Thomas A. Golper, Andrew A. Udy, and Jeffrey Lipman
- Section 18 Nephrology in the futureEdited by
Neil Turner
- Chapter 365 A global curriculum for training the next generation of nephrologists Tushar J. Vachharajani, Richard K. S. Phoon, and David C. H. Harris
- Chapter 366 Chronic Interstitial Nephritis in Agricultural CommunitiesChanna Jayasumana, Carlos Orantes, Marc E. De Broe
- End Matter
