Depression and Type 2 Diabetes

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Depression and Type 2 Diabetes

Edited by Khalida Ismail, Andreas Barthel, Stefan R. Bornstein, and Julio Licinio

Abstract

Type 2 diabetes is predicted to affect between 10% and 25% of the world population in the next 20 years. Depression is a common comorbid condition in those affected with type 2 diabetes, and the combination of these conditions is associated with a poorer prognosis, including earlier mortality. Genetic and epigenetic predisposition and overlap of risk factors related to our modern lifestyle seem to drive the shared biology of diabetes and depression. This book aims to provide an understanding of the sequelae of events leading to the frequent comorbidity of diabetes and depression. This book project has been supported by the transCampus of Kings College London and Technical University of Dresden. Chapter by chapter, internationally recognized clinicians and scientists have summarized the state of the art and outstanding controversies of the epidemiology, mechanisms, and treatment of the depression–type 2 diabetes comorbidity. This book is relevant for all health professionals including the general practitioner and specialist clinicians in internal medicine, endocrinology, diabetes and metabolic diseases, neurology, psychiatry, and psychology as well as students interested in this topic.

Bibliographic Information

Publisher:: Oxford University Press

Print Publication Date:: Aug 2018

Print ISBN-13:: 9780198789284

Published online:: Sep 2018

DOI:: 10.1093/med/9780198789284.001.0001

Authors

Khalida Ismail, editor Professor of Psychiatry and Medicine, Department of Psychological Medicine Institute of Psychiatry, Psychology and Neuroscience King's College London, London, UK

Andreas Barthel, editor Associate Professor of Medicine, Department of Medicine III, University Hospital Carl Gustav Carus, Dresden and Faculty of Medicine of the TU Dresden, Dresden, Germany

Stefan R. Bornstein, editor Professor of Medicine, Department of Medicine, University Hospital Carl Gustav Carus, Dresden and Faculty of Medicine of the TU Dresden, Dresden, Germany, Germany School of Life Course Sciences, Department of Diabetes, King's College London, London, UK

Julio Licinio, editor Deputy Director, College of Medicine, State University of New York, Upstate Medical University, Syracuse, USA

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Front Matter
- Preface
- Abbreviations
- Contributors
- Introduction
Chapter 1 Global burden of diabetes and depressionJulio Licinio, Andreas L. Birkenfeld, and Stefan R. Bornstein
Chapter 2 A life course approach to understanding the association between depression and type 2 diabetesKhalida Ismail, Calum D. Moulton, Andrea Danese, and Brenda W. Penninx
Chapter 3 MicroRNAs as novel biomarkers in depression, diabetes, and cardiovascular diseasesMohamad M. Almedawar, Richard C. Siow, and Henning Morawietz
Chapter 4 GeneticsCarol Kan and Ma-Li Wong
Chapter 5 Innate immunity and inflammation in type 2 diabetes-associated depressionCalum D. Moulton and John C. Pickup
Chapter 6 Hypothalamic–pituitary–adrenal axisAllan H. Young and Mario F. Juruena
Chapter 7 Gut–brain axis: Physiology and pathologyCarla Petrella, Giuseppe Nisticò, and Robert Nisticò
Chapter 8 Diabetes distressNorbert Hermanns, Marijke A. Bremmer, and Frank J. Snoek
Chapter 9 The association between depression and cognitive impairment in type 2 diabetesCalum D. Moulton and Clive Ballard
Chapter 10 Treatment of depression in type 2 diabetesFrank Petrak and Bonnie Röhrig
Chapter 11 Psychotropic drugs and metabolic riskAndreas Barthel and Michael Bauer
Chapter 12 Metabolic surgery and depressionLidia Castagneto Gissey, James R. Casella Mariolo, Geltrude Mingrone, and Francesco Rubino
Chapter 13 Novel pharmacological targetsCalum D. Moulton
Chapter 14 Novel technologies: What does gastric electrical stimulation offer to the patient with type 2 diabetes and depression?Harold E. Lebovitz and Shlomo Ben-Haim
Chapter 15 Current and emerging psychological modelsChristopher Garrett
Chapter 16 Targeting the circadian systemGregory D. M. Potter and Eleanor M. Scott
Chapter 17 Cultural and global perspectivesKirsty Winkley, Ebaa Al-Ozairi, and Boon-How Chew
Chapter 18 National and international policy initiatives on multimorbidityPeter E. H. Schwarz and Patrick Timpel
End Matter
- Index

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date: 16 April 2021

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Depression and Type 2 Diabetes

Edited by Khalida Ismail, Andreas Barthel, Stefan R. Bornstein, and Julio Licinio

Abstract

Bibliographic Information

Authors

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Contents