Autism Spectrum Disorders

Autism Spectrum Disorders

Edited by David Amaral, Daniel Geschwind, and Geraldine Dawson

Abstract

Autism is an emerging area of basic and clinical research, and has only recently been recognized as a major topic in biomedical research, and is now an intense growth area in behavioral and educational treatments. This resource provides a comprehensive summary of all current knowledge related to the behavioral, experiential, and biomedical features of the autism spectrum disorders, including major behavioral and cognitive syndromology, common co-morbid conditions, neuropathology, neuroimmunology, and other neurological correlates such as seizures, allergy and immunology, gastroenterology, infectious disease, and epidemiology.

Bibliographic Information

Publisher:: Oxford University Press

Print Publication Date:: May 2011

Print ISBN-13:: 9780195371826

Published online:: Sep 2012

DOI:: 10.1093/med/9780195371826.001.0001

Authors

David Amaral, editor Professor of Psychiatry and Neuroscience, The M.I.N.D. Institute, University of California at Davis

Daniel Geschwind, editor Professor of Neurology, Psychiatry and Human Genetics, David Geffen School of Medicine, University of California at Los Angeles

Geraldine Dawson, editor Chief Science Officer, Autism Speaks and Research Professor, University of North Carolina, Chapel Hill

Back to results

Print
Save
Cite
Email this content

Share Link

Copy this link, or click below to email it to a friend
Email this content
or copy the link directly:

https://oxfordmedicine.com/abstract/10.1093/med/9780195371826.001.0001/med-9780195371826
Link copied successfully

The link was not copied. Your current browser may not support copying via this button.
Share This

Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.

Front Matter
Introduction: Autism Turns 65: A Neurologist’s Bird’s Eye ViewIsabelle Rapin
Section I Historical Perspective, Diagnosis and Classification, and Epidemiology
- 1 Autism Spectrum Disorders: Looking Backward and Looking ForwardMichael Rutter
- 2 Diagnosis of Autism Spectrum DisordersKatherine Gotham, Somer L. Bishop, and Catherine Lord
- 3 Asperger’s Syndrome: From Asperger to Modern DayAmi Klin
- 4 Regression and Other Patterns of OnsetSally Ozonoff, Kelly Heung, and Meagan Thompson
- 5 Screening, Risk, and Early Identification of Autism Spectrum DisordersLonnie Zwaigenbaum
- 6 Epidemiology of Pervasive Developmental DisordersEric Fombonne, Sara Quirke, and Arlene Hagen
- 7 Culture and Autism Spectrum Disorders: The Impact on Prevalence and RecognitionRoy Richard Grinker, Marshalyn Yeargin-Allsopp, and Coleen Boyle
- Commentary: Issues in the Classification of Pervasive Developmental DisordersPatrick F. Bolton
Section II Core Features and Developmental Trajectories
- 8 The Social Behavior of Autism: A Parallel and Distributed Information Processing PerspectivePeter Mundy
- 9 Language and Communication in Autism Spectrum DisordersHelen Tager-Flusberg, Lisa Edelson, and Rhiannon Luyster
- 10 Cognitive and Neural Correlates of Language in AutismWouter B. Groen and Jan K. Buitelaar
- 11 Repetitive Behaviors in Individuals with Autism Spectrum DisordersJames W. Bodfish
- 12 Developmental Features and Trajectories Associated with Autism Spectrum Disorders in Infants and ToddlersRebecca J. Landa
- 13 Development from Preschool Through School AgeTony Charman
- 14 Adolescents and Adults with Autism Spectrum DisordersMarsha Mailick Seltzer, Jan S. Greenberg, Julie Lounds Taylor, Leann Smith, Gael I. Orsmond, Anna Esbensen, and Jinkuk Hong
- Commentary: Issues in Defining the Core Features of Autism Through the LifespanKatherine A. Loveland
Section III Psychiatric and Medical Comorbidities
- 15 Intellectual Disabilities and Autism Spectrum Disorder: A Cautionary NoteElisabeth M. Dykens and Miriam Lense
- 16 Comorbid Obsessive-Compulsive DisordersBonnie P. Taylor and Eric Hollander
- 17 Interface Between Autism Spectrum Disorders and Obsessive-Compulsive Behaviors: A Genetic and Developmental PerspectiveSuma Jacob, Angeli Landeros-Weisenberger, and James F. Leckman
- 18 Attention-Deficit/Hyperactivity Disorder (ADHD)Angela M. Reiersen and Richard D. Todd†
- 19 Specific Language ImpairmentJ. Bruce Tomblin, Karla McGregor, and Allison Bean
- 20 Anxiety and Mood Disorders in Individuals with Autism Spectrum DisorderPeter Szatmari and Beth McConnell
- 21 Stereotypy and Self-InjuryLindsey Sterling, Annie McLaughlin, and Bryan H. King
- 22 Motor Functioning and Dyspraxia in Autism Spectrum DisordersMatthew W. Mosconi, Yukari Takarae, and John A. Sweeney
- 23 Epilepsy and Electroencephalography in Autism Spectrum DisordersRoberto Tuchman
- 24 The Immune System, Autoimmunity, Allergy, and Autism Spectrum DisordersPaula Goines, Andrew Zimmerman, Paul Ashwood, and Judy Van de Water
- 25 Gastrointestinal Problems in Individuals with Autism Spectrum DisordersTimothy Buie
- 26 Sleep ProblemsAnne E. Porter and Daniel G. Glaze
- Perspective Article: Autism as a Medical DisorderChristopher Gillberg
Section IV Broader Autism Phenotype
- 27 The Broad Autism PhenotypeMolly Losh, Ralph Adolphs, and Joseph Piven
- 28 The Biological Broader Autism PhenotypeJanet E. Lainhart and Nicholas Lange
- 29 Autism as a Quantitative TraitJohn N. Constantino
- Commentary: The Broader Autism Phenotype: Implications for Research and Clinical PracticeJeremy R. Parr, Kerstin Wittemeyer, and Ann S. Le Couteur
Section V Neurobiology
- 30 Developmental Neurobiology of Autism Spectrum DisordersJohn L. R. Rubenstein
- 31 Neuropathology of Autism Spectrum Disorders: Postmortem StudiesCynthia M. Schumann, Steven C. Noctor, and David G. Amaral
- 32 NeurotransmittersDiane C. Chugani
- 33 Brain Chemistry: Magnetic Resonance SpectroscopyStephen R. Dager, Neva M. Corrigan, Todd W. Richards, and Dennis Shaw
- 34 Oxytocin, Vasopressin, and Social Behavior: Implications for Autism Spectrum DisordersMeera E. Modi and Larry J. Young
- 35 From Toddlers to Adults: The Changing Landscape of the Brain in AutismEric Courchesne, Sara Jane Webb, and Cynthia M. Schumann
- 36 Autism as a Developmental Neurobiological Disorder: New Insights from Functional NeuroimagingNancy J. Minshew, K. Suzanne Scherf, Marlene Behrmann, and Katherine Humphreys
- 37 Electrophysiological Research on AutismSara Jane Webb, Raphael Bernier, Karen Burner, and Michael Murias
- Commentary: Toward a Neurobiology of AutismPat Levitt
Section VI Etiology: Genetics
- 38 Whole Genome Linkage and Association AnalysesJanine A. Lamb
- 39 Autism Endophenotypes and Quantitative Trait LociRita M. Cantor
- 40 Autism Subgroups from a Medical Genetics PerspectiveJudith H. Miles
- 41 Rare Genetic Variants and Autism Spectrum DisordersHande Kaymakçalan and Matthew W. State
- 42 Known and Possible Roles of Epigenetics in AutismRichard Person, Xinna Zhang, Soeun Kim, Marwan Shinawi, and Arthur L. Beaudet
- 43 Isolated Populations and Common VariantsKarola Rehnström and Leena Peltonen†
- 44 Isolate Populations and Rare Variation in Autism Spectrum DisordersEric M. Morrow and Christopher A. Walsh
- 45 Rett Syndrome and MECP2-Related DisordersJeffrey L. Neul
- 46 Fragile X: A Molecular and Treatment Model for Autism Spectrum DisordersRandi J. Hagerman, Vivien Narcisa, and Paul J. Hagerman
- Commentary: Autism Genetics and Genomics: A Brief Overview and SynthesisDaniel H. Geschwind
Section VII Etiology: Environmental Factors
- 47 Environmental Risk Factors in Autism: Results from Large-Scale Epidemiologic StudiesIrva Hertz-Picciotto
- 48 Environmental Exposures That Increase the Risk of Autism Spectrum DisordersPatricia M. Rodier
- 49 Autism and Environmental Genomics: Synergistic Systems Approaches to Autism ComplexityMark A. Corrales and Martha R. Herbert
Section VIII Animal Models and Theoretical Perspectives
- 50 Zebrafish As a Tool to Study AutismAlicia Blaker-Lee, Gianluca De Rienzo, and Hazel Sive
- 51 Behavioral Evaluation of Genetic Mouse Models of AutismMu Yang, Maria Luisa Scattoni, Kathryn K. Chadman, Jill L. Silverman, and Jacqueline N. Crawley
- 52 Modeling Features of Autism in RodentsElaine Y. Hsiao, Catherine Bregere, Natalia Malkova, and Paul H. Patterson
- 53 Nonhuman Primate Models of AutismMelissa D. Bauman and David G. Amaral
- 54 Autism as a Disorder of Functional Brain ConnectivityRajesh K. Kana and Marcel Adam Just
- 55 The Extreme Male Brain Theory of Autism: The Role of Fetal AndrogensSimon Baron-Cohen, Bonnie Auyeung, Emma Ashwin, and Rebecca Knickmeyer, Michael Lombardo, Bhismadev Chakrabarti
- 56 The Mirror Neuron System and ImitationMarco Iacoboni
- 57 Information Processing and IntegrationKeith J. Yoder and Matthew K. Belmonte
- Commentary: Translation Between Different Types of ModelFrancesca Happé
Section IX Treatment Approaches
- 58 Applied Behavior Analysis and Early Intensive Behavioral InterventionTristram Smith
- 59 Naturalistic Approaches to Early Behavioral InterventionLaura Schreibman and Brooke Ingersoll
- 60 Relationship-Based Early Intervention Approach to Autistic Spectrum Disorders: The Developmental, Individual Difference, Relationship-Based Model (The DIR Model)Stanley I. Greenspan† and Serena Wieder
- 61 Intervention for Infants and Toddlers with Autism Spectrum DisordersSally J. Rogers and Katherine S. Wallace
- 62 Relationships, Independence, and Communication in Autism and Asperger’s DisorderLynn Kern Koegel, Rosy M. Fredeen, Robert L. Koegel, and C. Enjey Lin
- 63 Occupational TherapyLinn Wakeford and Grace T. Baranek
- 64 Augmentative and Alternative Communication SystemsMarjorie H. Charlop, Alissa L. Greenberg, and Gina T. Chang
- 65 Positive Behavior Support and Problem BehaviorEdward G. Carr†
- 66 Social Skills Interventions for Children With Autism Spectrum DisordersConnie Kasari and Jill Locke
- 67 Adolescent Transition to Adulthood and Vocational IssuesRobin L. Gabriels
- 68 Family Adaptive Functioning in AutismAnnette Estes, Vanessa Hus, and Lauren Elder
- 69 Psychopharmacological Treatment of AutismKelly Blankenship, Craig A. Erickson, Kimberly A. Stigler, David J. Posey, and Christopher J. McDougle
- 70 Autism Spectrum Disorders: Identification and Implications of Associated Medical ConditionsMargaret L. Bauman
- 71 Dietary, Complementary, and Alternative TherapiesSusan L. Hyman and Susan E. Levy
- 72 The mGluR Theory of Fragile X SyndromeDilja D. Krueger and Mark F. Bear
- Commentary: Future Directions in the Treatment of Autism Spectrum DisordersEvdokia Anagnostou, Mark F. Bear, and Geraldine Dawson
Section X Best Practices in the Diagnosis and Treatment of Autism
- 73 Best Practices: Early Diagnosis and Psychological AssessmentZachary Warren and Wendy L. Stone
- 74 Diagnosis and Assessment of Autism Spectrum Disorders: A Medical PerspectiveDaniel L. Coury
- 75 Best Practice, Policy, and Future Directions: Behavioral and Psychosocial InterventionsKara Hume and Samuel L. Odom
- 76 Pharmacotherapy for Autism Spectrum DisordersJames T. McCracken
- 77 Best Practices: PediatricsMary Catherine Aranda and Sarah J. Spence
- Commentary: Bioethical Considerations in Autism Research and Translation: Present and FutureHolly K. Tabor
Section XI Public Policy
- 78 The Economic Costs of Autism: A ReviewDjesika Amendah, Scott D. Grosse, Georgina Peacock, and David S. Mandell
- 79 Future Directions: Setting Priorities to Guide the Federal Research EffortThomas R. Insel and Susan A. Daniels
- 80 To Petition the Government for a Redress of GrievancesCraig Snyder and Peter H. Bell
- 81 Top Priorities for Autism/Asperger’s Research: Perspectives from a Person with AutismTemple Grandin
End Matter
- Index

Browse All

Browse All

Browse All

Autism Spectrum Disorders

Edited by David Amaral, Daniel Geschwind, and Geraldine Dawson

Abstract

Bibliographic Information

Authors

Share Link

Contents

Browse All

Browse All

Browse All

Recently viewed (0)

Recently viewed (0)

Autism Spectrum Disorders

Edited by David Amaral, Daniel Geschwind, and Geraldine Dawson

Abstract

Bibliographic Information

Authors

Share Link

Contents