Psychiatric Genetics: A Primer for Clinical and Basic Scientists

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Psychiatric Genetics: A Primer for Clinical and Basic Scientists

Edited by Thomas Schulze and Francis McMahon

Abstract

Psychiatric Genetics: A Primer for Clinical and Basic Scientists provides a straightforward introduction to the essentials of psychiatric genetics, complementing available comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders of the International Society of Psychiatric Genetics (ISPG), the main goal of this book is to educate clinicians and scientists about psychiatric genetics, as psychiatrists and other mental health care professionals are increasingly confronted with questions about genetics, psychiatric illness, and the clinical applications of new genetic findings. The book covers all major aspects of psychiatric genetics, including basic epidemiology, recruitment for human studies, phenotyping strategies, formal genetic and molecular genetic studies, statistical genetics, bioinformatics and genomics, pharmacogenetics, the most relevant animal models, and biobanking. Each chapter begins with a list of “take home” points that summarizes content, followed by a brief overview of current knowledge and suggestions for further reading. This Primer is ideal for medical students, psychiatric residents, psychiatrists, and basic neuroscience researchers who are interested in learning the basic concepts of psychiatric genetics and the advances in the field.

Bibliographic Information

Publisher:: Oxford University Press

Print Publication Date:: Apr 2018

Print ISBN-13:: 9780190221973

Published online:: May 2018

DOI:: 10.1093/med/9780190221973.001.0001

Authors

Thomas Schulze, editor Professor of Psychiatric Genetics, University of Gottingen

Francis McMahon, editor Chief, Human Genetics Branch, National Institute of Mental Health Intramural Research, NIH

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Front Matter
- Preface
- Contributors
Chapter 1 Contribution of Epidemiology to Our Understanding of Psychiatric GeneticsAlison K. Merikangas and Kathleen R. Merikangas
Chapter 2 Recruitment of Human Subjects: An Overview of Techniques and Methods Used in Psychiatric and Other Clinical StudiesLayla Kassem
Chapter 3 Basic Molecular Genetics Concepts and Tools: From SNPs to ChipsSevilla D. Detera-Wadleigh, Nirmala Akula, and Liping Hou
Chapter 4 Statistical Genetics: Genome-Wide StudiesTill F. M. Andlauer, Bertram Müller-Myhsok, and Stephan Ripke
Chapter 5 Human Linkage and Association AnalysisJohn P. Rice
Chapter 6 The Role of Copy Number Variation in Psychiatric DisordersElliott Rees and George Kirov
Chapter 7 Pharmacogenomics and Precision PsychiatryJulia C. Stingl and Gonzalo Laje
Chapter 8 EndophenotypesDavid C. Glahn, Laura Almasy, and John Blangero
Chapter 9 Imaging GeneticsLuanna Dixson, Heike Tost, and Andreas Meyer-Lindenberg
Chapter 10 Bioinformatics in Psychiatric GeneticsNikola S. Mueller, Ivan Kondofersky, Gökcen Eraslan, Karolina Worf, and Fabian J. Theis
Chapter 11 Epigenomic Exploration of the Human BrainTobias B. Halene, Gregor Hasler, Amanda Mitchell, and Schahram Akbarian
Chapter 12 Epigenetics in PsychiatrySubha Subramanian and James B. Potash
Chapter 13 Next-Generation Sequencing in Genetic Studies of Psychiatric DisordersShweta Ramdas and Jun Z. Li
Chapter 14 Animal ModelsTadafumi Kato
Chapter 15 Biobanking of Human Induced Pluripotent Stem Cells for Psychiatric ResearchJennifer C. Moore, Michael Sheldon, and Jay A. Tischfield
End Matter
- Index

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date: 14 April 2021

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Psychiatric Genetics: A Primer for Clinical and Basic Scientists

Edited by Thomas Schulze and Francis McMahon

Abstract

Bibliographic Information

Authors

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Contents