Handbook of Child and Adolescent Tuberculosis

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Handbook of Child and Adolescent Tuberculosis

Edited by Jeffrey R. Starke and Peter R. Donald

Abstract

While there have been a large number of recent textbooks dealing with tuberculosis in adults, usually with minimal or no content relevant to pediatrics, and there have been several textbooks on childhood tuberculosis with distribution limited mostly to India and South Africa, there has not been a widely distributed book on childhood tuberculosis since 1963. We have assembled a group of internationally recognized clinicians, researchers and authors to create a modern handbook of childhood tuberculosis. This book covers all aspects of childhood tuberculosis including: the natural history of childhood tuberculosis and the history of its scientific study; microbiology and laboratory testing for Mycobacterium tuberculosis and Mycobacterium bovis; epidemiology; clinical and radiographic presentations of intra- and extra-thoracic tuberculosis; diagnosis and treatment of tuberculosis infection; diagnosis and treatment of drug-susceptible and drug-resistant tuberculosis disease; management of tuberculosis in newborns, adolescents and children with HIV infection; BCG vaccines; public health and infection control aspects of childhood tuberculosis; and the World Health Organization Roadmap for Childhood Tuberculosis. We highlight those aspects of tuberculosis that are unique to children and adolescents and principles that have practical applications through the use of algorithms, figures and tables to emphasize key points and encourage standardization of practice, when possible. This book is intended for use by clinicians, researchers and policy makers to ensure that the needs of children and adolescents with tuberculosis are met throughout the world.

Bibliographic Information

Publisher:: Oxford University Press

Print Publication Date:: Dec 2015

Print ISBN-13:: 9780190220891

Published online:: Mar 2016

DOI:: 10.1093/med/9780190220891.001.0001

Authors

Jeffrey R. Starke, editor Director, Children's Tuberculosis Clinic, Texas Children's Hospital

Peter R. Donald, editor Emeritus Professor of Paediatrics and Child Health, Stellenbosch University

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Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

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Front Matter
- Epigraph
- Dedication
- Preface
- About the Editors
- Abbreviations
- Contributors
1 A Brief History of Childhood Tuberculosis Peter R. Donald
2 Microbiology and Pathology of Tuberculosis Anne-Marie Demers, Andrew C. Whitelaw, and Kathleen D. Eisenach
3 Immunology of Tuberculosis in Children Beate Kampmann and Elizabeth Whittaker
4 Natural History of Childhood Tuberculosis Ben J. Marais
5 Global Epidemiology of Pediatric Tuberculosis Charalambos Sismanidis, Philippe Glaziou, Malgosia Grzemska, Katherine Floyd, and Mario Raviglione
6 Diagnosis of Tuberculosis Infection in Children Anna M. Mandalakas and Andrew DiNardo
7 Microbiological Diagnosis of Pulmonary Tuberculosis in Children Mark P. Nicol and Heather J. Zar
8 Radiology of Childhood Tuberculosis Savvas Andronikou and Tracy Kilborn
9 Diagnosis of Intrathoracic Tuberculosis in Children Carlos M. Perez-Velez
10 Diagnosis of the Most Common Forms of Extrathoracic Tuberculosis in Children H. Simon Schaaf and Anthony J. Garcia-Prats
11 Central Nervous System Tuberculosis in Children Ronald van Toorn
12 Tuberculosis in Adolescents Andrea T. Cruz
13 Tuberculosis in Neonates and Infants Adrie Bekker
14 Tuberculosis in HIV-Infected and Exposed Infants, Children, and Adolescents Helena Rabie and Mark F. Cotton
15 Antituberculosis Drugs in Children Helen McIlleron
16 Treatment of Tuberculosis Infection in Children Amina Ahmed
17 Management of Drug-Susceptible Tuberculosis in Children Soumya Swaminathan and N. Poorana Ganga Devi
18 Management of Drug-Resistant Tuberculosis in Children James Seddon
19 Bacille Calmette–Guérin Vaccines Kim Connelly Smith, Ian M. Orme, and Jeffrey R. Starke
20 Mycobacterium Bovis (non-BCG) in Children Jeffrey R. Starke
21 Public Health and Programmatic Issues for Childhood Tuberculosis Jeffrey R. Starke
22 The Roadmap for Childhood Tuberculosis Stephen M. Graham and Anne Detjen
End Matter
- Index

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date: 14 April 2021

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Edited by Jeffrey R. Starke and Peter R. Donald

Abstract

Bibliographic Information

Authors

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Contents