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- Chapter 1 Jeremiah Barker: Background, Education, and Writings
- Chapter 2 Obtaining and Sharing Medical Literature, 1780–1820
- Chapter 3 The Old Medicine and the New: Why Did Barker Write This Manuscript, for Whom Was It Written, and Why Was It Not Published?
- Chapter 4 “Alkaline Doctor” and “A Dangerous Innovator”
- Chapter 5 Thoughts to Consider While Reading Barker’s Manuscript: Presentism, Whiggish History, and the Post Hoc Fallacy