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Social Outcome Following Early-Life Damage to Prefrontal Cortex 

Social Outcome Following Early-Life Damage to Prefrontal Cortex
Chapter:
Social Outcome Following Early-Life Damage to Prefrontal Cortex
Author(s):

Steven W. Anderson

, and Daniel Tranel

DOI:
10.1093/med/9780199837755.003.0032
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date: 18 December 2018

Chapter 27 discusses how circumscribed damage to the prefrontal cortex (PFC) during the first few years of life results in the development of a primary social defect in the context of generally normal intellectual abilities, and how these neuropsychological impairments often persist into adulthood, and may be more severe than the consequences of similar injuries acquired later in life, due to developmental disruption of the acquisition of complex social conventions and moral rules. It then discusses how the long-term outcome can be optimized through early and sustained intervention involving environmental structuring, contingency management, and cognitive-behavioral instruction.

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