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Glia–Neuron Interactions in Ictogenesis and Epileptogenesis: Role of Inflammatory Mediators 

Glia–Neuron Interactions in Ictogenesis and Epileptogenesis: Role of Inflammatory Mediators
Chapter:
Glia–Neuron Interactions in Ictogenesis and Epileptogenesis: Role of Inflammatory Mediators
Author(s):

Annamaria Vezzani

, Stephan Auvin

, Teresa Ravizza

, and Eleonora Aronica

DOI:
10.1093/med/9780199746545.003.0048
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date: 16 July 2018

This chapter reports clinical observations in drug-resistant epilepsies and experimental findings in adult and immature rodent models of seizures and epileptogenesis that causally link brain inflammation to the epileptic process. We discuss the role of specific inflammatory mediators of glia–neuron communication in the etiopathogenesis of seizures.

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