Show Summary Details
Page of

The applicability of trials of complex mental health interventions 

The applicability of trials of complex mental health interventions
The applicability of trials of complex mental health interventions

Lara Fairall

, Merrick Zwarenstein

, and Graham Thornicroft

Page of

PRINTED FROM OXFORD MEDICINE ONLINE ( © Oxford University Press, 2016. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy and Legal Notice).

date: 12 November 2018

The evidence on what interventions are currently known to be effective in mental health is summarized in the 2009 PLoS Medicine series on packages of care for mental, neurological, and substance-use disorders in LAMIC and the WHO mhGAP guidelines published in 2010. But far less is known about how best to deliver and scale-up these interventions in real-life settings. How to translate this evidence into practice, in ways that are culturally appropriate and sensitive has been identified as the key research priority in global mental health. This chapter discusses the potential contribution of trials to the genesis of interventions that are both effective and highly applicable to real-world settings by considering two frameworks : the development–evaluation–implementation process proposed by the Medical Research Council (MRC) in Britain in their 2000 and 2008 guidance on developing and evaluating complex interventions and the PRagmatic Explanatory Continuum Indicator Summary (PRECIS) tool.

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.