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Trials for people with mental disorders and conditions associated with stress 

Trials for people with mental disorders and conditions associated with stress
Chapter:
Trials for people with mental disorders and conditions associated with stress
Author(s):

Wietse A. Tol

, Mark J.D. Jordans

, Dessy Susanty

, and Joop T.V.M. de Jong

DOI:
10.1093/med/9780199680467.003.0013
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date: 23 November 2017

Exposure to negative life events is associated with worse mental health outcomes. The chapter provides an overview of mental disorders and conditions specifically associated with stress. It discusses proposals for a new category of conditions and disorders specifically associated with stress (e.g. symptoms of acute stress, post-traumatic stress disorder (PTSD), complex PTSD, prolonged grief disorder, adjustment disorder) and summarizes recent guidance for interventions. A preventive school-based intervention with children affected by armed conflict and cluster randomized trial in Indonesia is described and findings compared with trials in Burundi, Nepal, and Sri Lanka. These studies showed diverse effects of the same preventive intervention in different contexts and for different sub-populations. In accordance with a socioecological framework, intervention results were dependent on the extent to which children were exposed to ongoing events and the level of support they could draw on.

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