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Trials of interventions for people with depression 

Trials of interventions for people with depression
Chapter:
Trials of interventions for people with depression
Author(s):

Neerja Chowdhary

, Atif Rahman

, Helena Verdeli

, and Vikram Patel

DOI:
10.1093/med/9780199680467.003.0010
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date: 23 November 2017

Depression is a global health priority. Despite the evidence on burden and effective treatments, the vast majority of individuals affected by depression do not receive these treatments. Major challenges exist for implementation of evidence-based treatments, especially in LAMIC. A number of clinical trials have shown the effectiveness of treatment for depression across a range of low-resource settings and the common threads running through these trials. MANAS is one such trial conducted in Goa, India, which provided evidence that trained lay counsellors working within a collaborative-care model can reduce prevalence of common mental disorder, suicidal behaviour, psychological morbidity, and disability days among those attending public primary care facilities. Despite the additional resources required for the intervention, costs incurred over follow-up were similar across the two arms. The role that lay health workers can play in reducing the treatment gap has important implications for mental health care in low-resource settings.

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