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Alzheimer’s disease 

Alzheimer’s disease
Chapter:
Alzheimer’s disease
Author(s):

John-Paul Taylor

and Alan Thomas

DOI:
10.1093/med/9780199644957.003.0033
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date: 25 November 2017

Alzheimer’s disease (AD) is a well recognised clinicopathological entity and the most common cause of dementia. This chapter critiques the several sets of newly proposed criteria for making the diagnosis of (AD) at different stages in the disease process, in the context of demand for earlier diagnosis and emerging biomarkers. The differential diagnosis and types of different cognitive symptoms are reviewed and the prevalence and pattern of the many non-cognitive symptoms associated with AD are considered. The management of non-cognitive symptoms is also updated, especially the circumstances in which antipsychotic drugs might be prescribed. And finally a summary of our current understanding of the aetiology (evidence for risk and protective factors for AD ) and the prognosis for AD is provided.

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