Amendments and Errata to Eighth Edition
Middle box, 3rd paragraph, last sentence: This is no longer applicable, as sibutramine has since been discontinued.
The most recent reprint of OHCM 8th Edition has been updated to reflect the new guidelines issued by the UK Resuscitation Council in October 2010. Keep abreast of new guidelines at http://www.resus.org.uk/pages/guide.htm.
Figure 2 (lung anatomy) has been updated – click here to see the new image.
Within the ‘Administering oxygen’ box, under ‘Venturi mask,’ the text in the table should read White: 28% and Yellow: 35% not White: 8% and Yellow: 5%.
The third bullet point after the second heading should read Microalbuminuria is when urine dipstick is –ve for protein but the urine albumin:creatinine ratio (UCR) is Ã‚Â²3mg/mmol (p771) reflecting early renal disease and ^ vascular risk. If UCR >3, inhibiting the renin-angiotensin system, even if BP is normal, protects the kidneys... not Microalbuminuria is when urine dipstick is –ve for protein but the urine albumin:creatinine ratio (UCR) is Ã‚Â²30mg/mmol (p771) reflecting early renal disease and ^ vascular risk. If UCR >30, inhibiting the renin-angiotensin system, even if BP is normal, protects the kidneys.
The last sentence of the third bullet point after the second heading should read Refer if UCR > 7 Ã‚Â± GFR falling by >5mL/min/1.73mÃ‚Â²/yr not Refer if UCR > 70 Ã‚Â± GFR falling by >5mL/min/1.73mÃ‚Â²/yr.
Table - second column, 3rd heading: should read (or benzylpenicillin 1.2g IM/IV stat if outside hospital) and not (or benzylpenicillin 1.2mg IM stat if outside hospital).
After the heading ‘Shingles’, end of first sentence should read eg 800mg 5 times/d PO for 5-7d if eGFR >25. and not eg 800mg 5 times/d PO for 5-7d if eGFR <25.
The text after ‘Blood film’ should read Blood fim shows a lymphocytosis (Ã‚Â²45% of WBC) and atypical lymphocytes... and not Blood fim shows a lymphocytosis (~20% of WBC) and atypical lymphocytes....
The figure has been updated – click here to see the new image.
The text after ‘Signs’ should read Ask the patient to wrinkle up the forehead and close the eyes forcefully (under bilateral cortical control, thus spared in UMN lesions) and not Ask the patient to wrinkle up the forehead and close the eyes forcefully (bilaterally innervated and thus spared in a LMN lesion).
Two lines below the second red-bordered box, ‘Causes of ascites’, it should read with a 21G needle in LIF, not with a 21G needle in RIF.
The text after ‘Recurrent UTIs’ should read (in magnesium ammonium phosphate calculi) and not (in magnesium aluminium phosphate calculi).
The third line under the heading ‘Urinary proteins’ should read protein loss between 30 and 300mg/d, not protein loss between 3 and 300mg/d.
The tenth entry in the bottom table (protein) should be followed by the entry Protein:creatinine ratio (see p309) <3mg/mmol.
The first blue bullet-point of the ‘Antibiotic therapy for meningitis’ box should read <55yrs: cefotaxime 2g/6h slow IV, not <55yrs: cefotaxime 2mg/6h slow IV.
The first bullet point under the lowest heading, ‘Urgent dialysis if’, should read K+ persistently high (>7.0mmol/L), not K+ persistently high (>6.0mmol/L).
The paragraph following ‘Carbon monoxide’ should be replaced by the paragraph CO binds reversibly to Hb to form carboxyhaemoglobin (COHb) which shifts the O2 dissociation curve to the left and down, impairing tissue oxygenation. The PaO2 is normal, but SaO2 is reduced (appears normal if calculated from the PaO2 eg blood gas analyser). However, since CoHb is red the skin often appears pink, or rarely ‘cherry red’. Breathing 100% O2, or use of a hyperbaric chamber, dramatically increases the rate at which CO is displaced from Hb..