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Other causes of pulmonary hypertension 

Other causes of pulmonary hypertension
Chapter:
Other causes of pulmonary hypertension
Author(s):

Sara Goletto

, Ryo Inuzuka

, and Koichiro Niwa

DOI:
10.1093/med/9780199572632.003.0011
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date: 15 August 2018

Patients with HIV and pulmonary arterial hypertension (PAH) have an increased risk of death compared to those without. Bosentan has been shown to improve functional capacity without interfering with antiretroviral drug plasma concentrations

Chronic schistosomiasis is one of the most common causes of PAH in endemic areas. A high index of suspicion is necessary when patients from such areas are presented with symptoms suggesting possible pulmonary hypertension

In patients with portal hypertension, the risk of developing pulmonary arterial hypertension increases with the duration of the disease. Screening for PAH is recommended if liver transplantation is considered

The prevalence of PAH amongst patients with sickle cell disease is about 30% and significantly reduces survival. Right heart catheterization is recommended In suspected cases to confirm the diagnosis of PAH and rule out pulmonary venous hypertension due to left heart disease, which is often present in this population.

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