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Haemodynamics and treatment approaches in PH due to left heart disease 

Haemodynamics and treatment approaches in PH due to left heart disease
Chapter:
Haemodynamics and treatment approaches in PH due to left heart disease
Author(s):

Clive Handler

and Gerry Coghlan

DOI:
10.1093/med/9780199572564.003.025
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date: 21 September 2018

Introduction 120

Disproportionate post-capillary PH 120

Presentation of post-capillary PH 120

Diagnosis of post-capillary PH 121

Treatment of post-capillary PH 121

Chronic left heart failure leads to haemodynamic, autonomic, neurohumoral, and immunological abnormalities. There is activation of cytokines and inflammatory markers. It is unclear whether secondary mechanisms such as endothelial damage can result in an independent pulmonary vasculopathy in patients with heart failure....

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