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Staging, classification, and natural history of HIV disease 

Staging, classification, and natural history of HIV disease
Staging, classification, and natural history of HIV disease

Pauline Handy MBE

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date: 21 September 2018

Clinical staging 430

Natural history of untreated HIV infection 432

Early in the epidemic, before HIV was discovered, diagnosis of AIDS was largely based on finding Pneumocystis jiroveci (previously P.carinii) pneumonia (PCP) or Kaposi’s sarcoma. HIV antibody testing led to patients being identified as having asymptomatic infection, AIDS-related complex, or AIDS. The Centers for Disease Control and Prevention (CDC) devised a classification system, revised in 1993, based on clinical features, AIDS-defining illnesses, and CD4 counts (...

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