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OCL Lipid Disorders$
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OCL Lipid Disorders

Paul Nicholls, Ian Young

Publisher:
Oxford University Press
Print Publication Date:
Mar 2009
Print ISBN-13:
9780199569656
Published to Oxford Medicine:
May 2011
DOI:
10.1093/med/9780199569656.001.0001

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Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Hypercholesterolaemia and risk assessment

Chapter:
Hypercholesterolaemia and risk assessment
Author(s):

Paul Nicholls,

Ian Young

DOI:
10.1093/med/9780199569656.003.0006

• In patients with established vascular disease or very high risk (secondary prevention), the aim should be to reduce total cholesterol (TC) to <5 mmol/L and low-density lipoprotein cholesterol (LDL-C) to <3 mmol/L.

• Ideal levels are TC <4 mmol/L and LDL-C <2 mmol/L, but these may not be achievable in everybody.

• In patients with no known vascular disease (primary prevention), the decision to treat depends on the individual ’ s risk profile, but the targets are the same.

• A holistic approach includes assessment of other risk factors as well, such as hypertension, smoking, diabetes, or obesity.

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