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Current trials in renal cell carcinoma 

Current trials in renal cell carcinoma
Chapter:
Current trials in renal cell carcinoma
Author(s):

Paul Nathan

and Anup Vinayan

DOI:
10.1093/med/9780199562312.003.0009
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date: 20 November 2017

• The advent of clinically useful targeted therapies for renal cell carcinoma (RCC) has resulted in a large expansion in clinical trial activity • Current trials focus on identifying optimal sequences and combinations of new agents as well as determining whether the new agents are active in the adjuvant setting • An understanding of mechanisms of resistance to targeted agents would inform the optimal use of new agents • Given the large number of possible combinations and sequences of new therapies that need to be assessed, innovative approaches to clinical trial design need to be considered.

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