Symbols and abbreviations
AA
Anti-androgen
ADT
Androgen deprivation therapy
AR
Androgen receptor
ASCO
American Society of Clinical Oncology
BCR
Biochemical recurrence
BFGF
Basic fibroblast growth factors
CAB
Combined androgen blockade
CML
Chronic myeloid leukemia
CPA
Cyproterone acetate
CRPC
Castration-resistant prostate cancer
CSDX
Casodex®
CTC
Circulating tumor cell
DES
Diethylstilbestrol
DHT
5(-dihydrotestosterone
EDTMP
Ethylenediaminetetramethylene phosphonic aci
EGF
Epidermal growth factor
EMP
Estramustine phosphate
EPCP
Early Prostate Cancer Programme
EORTC
European Organisation for Research and Treatment of Cance
ERBT
External beam radiotherap
FDA
Food and Drug Administratio
GnRH
Gonadotropin-releasing hormon
HEDP
Hydroxyethylene diphosphonat
HPG
Hypothalamic-pituitary-gonadal
HSP
Heat shock proteins
IGF-I
Insulin-like growth factor-
IL-6
Interleukin-6
KGF
Keratinocyte growth factor
LH
Luteinizing hormone
LHRH
Luteinizing hormone releasing hormone
MAPK
Mitogen activated protein kinase
MRC
Medical Research Council
NICE
National Institute for Health and Clinical Excellenc
PCTCG
Prostate Cancer Trialists’ Collaborative Grou
PCWG
Prostate Cancer Working Grou
PDGF
Platelet derived growth factors
PKA
Protein kinase A
PKC
Protein kinase C
PPI
present pain intensity
PSA
Prostate specific antigen
PSADT
PSA doubling tim
SPARC
Satraplatin and Prednisone Against Refractory Cancer
SRE
Skeletal related event
SSRI
Selective serotonin reuptake inhibitors
SWOG
Southwest Oncology Group
VEGF
Vascular endothelial growth factor