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Advanced diabetic eye disease 

Advanced diabetic eye disease
Chapter:
Advanced diabetic eye disease
Author(s):

Karen Whitehouse

DOI:
10.1093/med/9780199544967.003.0008
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date: 16 October 2017

• Hypoxia of the retina leads to development of new vessels which subsequently may form fibrous and glial tissue. • Gliosis and fibrosis in the new vessels from the retina onto the posterior vitreous interface may cause retinal traction and retinal detachment. • New blood vessels can also grow into the angle of the anterior chamber of the eye (rubeosis iridis) leading to neovascular or rubeotic glaucoma. • Rubeotic glaucoma is a serious complication with visual loss and raised intra-ocular pressure, resulting eventually in acute severe periorbital pain, corneal oedema, and optic atrophy. • Advanced diabetic eye disease can remain asymptomatic for a long time, due to the slow progression of proliferative retinopathy. • Diabetic retinopathy screening is an important factor in early identification and following timely laser, may prevent development of advanced disease.

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