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Chemotherapy 

Chemotherapy
Chapter:
Chemotherapy
DOI:
10.1093/med/9780199299676.003.12
Page of

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date: 25 April 2018

General principles 132

Pharmacological principles 134

Phases of cell cycle 135

Classes of cytotoxic drugs 136

Characteristics of cytotoxic drugs 138

Most chemotherapy protocols for childhood malignancies employ combinations of two or more cytotoxic drugs. Combination chemotherapy aims to take advantage of:

Different mechanisms of action, which may be complementary....

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