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Oxford Textbook of Endocrinology and Diabetes$
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Oxford Textbook of Endocrinology and Diabetes (2 ed.)

Edited by John A.H. Wass, Paul M. Stewart, Stephanie A. Amiel, Melanie C. Davies

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Publisher:
Oxford University Press
Print Publication Date:
Jul 2011
Print ISBN-13:
9780199235292
Published to Oxford Medicine:
Jul 2011
DOI:
10.1093/med/9780199235292.001.1

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Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Contents

Premenstrual syndrome

Chapter:
Premenstrual syndrome
Author(s):

Andrea Andrea,

Mya Zapata

DOI:
10.1093/med/9780199235292.003.0825

The premenstrual disorders, premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) are psychoneuroendocrine disorders characterized by a constellation of affective, somatic, and behavioural symptoms that occur monthly, during the luteal phase of the menstrual cycle with relief soon after the onset of menses. PMS affects approximately 15–40% of reproductive aged women depending on criteria for diagnosis. PMDD is a severe form of PMS, with an emphasis on the affective symptoms. It has been estimated that only 5–8% of women meet the strict criteria for PMDD, but up to 20% may be one symptom short of meeting the criteria (1). The premenstrual syndromes adversely impact relationships, activities of daily living, and workplace productivity.

The research and treatment of the premenstrual disorders have been hampered by lack of consensus regarding the specific diagnostic criteria, methods of assessment of symptoms and impairment, and absence of animal models or biological markers for the disorders. However, elucidation of various aspects of the pathophysiology, well designed multicentre treatment trials, and patient and clinician education have successfully improved diagnosis and management This chapter will review symptoms, definitions, diagnostic criteria, aetiology, evaluation, and nonpharmacological and pharmacological management of PMS and PMDD.

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