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Oxford Textbook of Endocrinology and Diabetes$
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Edited by John A.H. Wass, Paul M. Stewart, Stephanie A. Amiel, Melanie C. Davies

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Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Contents

Depression and diabetes mellitus

Chapter:
Depression and diabetes mellitus
Author(s):

Khalida Ismail,

Frank Petrak

DOI:
10.1093/med/9780199235292.003.1574

There is a high prevalence of co-morbid depression in people with diabetes. Depression is a mental disorder that is associated with worse physical outcomes in diabetes, in particular higher rates of diabetes complications and mortality, but it is often undetected and undertreated. The mechanisms underlying the high rates of depression and its adverse effects are not well understood but appear to include both biological and psychological processes. Depression may have a more chronic course in people with diabetes compared to those without diabetes. The current evidence for the treatment of depression in diabetes suggests that treating depression improves mood but its effectiveness in improving glycaemic control is poor.

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