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Genetics of type 2 diabetes mellitus 

Genetics of type 2 diabetes mellitus
Chapter:
Genetics of type 2 diabetes mellitus
Author(s):

Niels Grarup

, Torben Hansen

, and Oluf Pedersen

DOI:
10.1093/med/9780199235292.003.1329
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date: 19 August 2018

For years, it has been well known that genetic factors are crucially important for the development of type 2 diabetes. Despite major efforts in seeking to understand the molecular genetic basis, until a few years ago, only a handful of genes responsible for relatively rare monogenic and syndromic subsets of diabetes were detected, and progress in finding genetic predispositions to common type 2 diabetes was lacking. Even though the unravelling of the molecular pathogenesis of type 2 diabetes is still in its infancy, the last few years have, nevertheless, brought some interesting developments. Box 13.3.1.1 provides a glossary of terms used currently in genetics.

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