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Pathophysiological changes of ageing and their relevance to anaesthesia 

Pathophysiological changes of ageing and their relevance to anaesthesia
Chapter:
Pathophysiological changes of ageing and their relevance to anaesthesia
Author(s):

Chris Dodds

, Chandra M. Kumar

, and Frédérique Servin

DOI:
10.1093/med/9780199234622.003.0002
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date: 21 October 2017

Organ function declines at an average rate of 1% a year from the age of 40.

Behavioural influences (choosing not to drink for instance) have to be considered.

Atrial fibrillation (AF) is the default rhythm for the elderly.

Closing volume lies within tidal ventilation when supine after the age of 65.

Muscles are no longer ‘vessel-rich’.

Autonomic dysfunction may be occult but should be sought.

Renal homeostasis is reduced in both speed and degree of compensation to water and solute loads.

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