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Physiology of obesity, molecular, and medical approaches 

Physiology of obesity, molecular, and medical approaches
Chapter:
Physiology of obesity, molecular, and medical approaches
Author(s):

Mark Bellamy

and Michel Struys

DOI:
10.1093/med/9780199233953.003.0002
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date: 20 October 2017

• Many overweight and obese people have an extremely negative body image. • Poor body image may contribute to the persistence of obesity. • Reduction in activity and increased calorie consumption are obligatory consequences of obesity, not simply causes of obesity. • The pathways of energy balance represent a three limb process, orchestrated by the hypothalamus. • There is probably a strong individual genetic component, with everyone having their own ‘leptin set point’. • Medical strategies include behaviour and lifestyle modification, and drug therapy. • The contribution of pharmacological therapy is limited.

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