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Oxford Textbook of Medicine$
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Edited by David A. Warrell, Timothy M. Cox, John D. Firth

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Latest update

The November 2012 update sees updates to over 70 chapters, focusing on Neurology and Gastroenterology. This update also incorporates a selection of 29 Case Histories taken from related titles in the Oxford Case Histories series, linked to from related chapters. Each case includes several questions followed by detailed answers and discussion to enhance diagnostic and clinical understanding.

Neurology updates include substantial updates to key chapters and new material on a wide range of topics including spinal cord injury, autonomic nervous system disorders, and inherited neurodegenerative diseases. 

Gastroenterology updates
include extensive revisions of key chapters on liver failure and acute pancreatitis and new material on a wide range of matters, ranging from the common to the rare: including surgical treatments for colonic diverticular disease, antibody tests for immune disorders, and a revised treatment algorithm for small bowel bacterial overgrowth.

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Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Contents

Grief, stress, and post-traumatic stress disorder

Chapter:
Grief, stress, and post-traumatic stress disorder
Author(s):

Tim Dalgleish,

Jenny Yiend,

Ann-Marie J. Golden

DOI:
10.1093/med/9780199204854.003.260501

Grief—this is the constellation of psychological responses to the loss of a loved one. Normal grief arguably develops in stages and dissipates in strength and impact over time. Some people (14–34%) suffer from pathological grief, where intense emotional distress and impairment of functioning persist for 6 months or more. This is often comorbid with other psychiatric disorders. Grief—and pathological grief in particular—carry an increased risk of mortality in the bereaved person, hence treatment of pathological grief using psychological therapy is advised.

Stress—the term can refer either to an external object, event, or situation that is the source of ongoing emotional distress, or to the constellation of psychological responses, dominated by elevated physiological arousal, that comprise an individual’s subjective experience in response to such stimuli. A subdiagnostic level of stress is common and is a risk factor for numerous physical health problems. Stress of this nature can frequently be ameliorated by lifestyle changes.

Pathological stress responses—these include acute stress disorder and post-traumatic stress disorder (PTSD), which occur in response to extremely stressful events. PTSD is characterized by (1) re-experiencing of the stressful event—e.g. nightmares, images, and flashbacks; (2) sustained avoidance of reminders of the event or of stimuli that might trigger re-experiencing; and (3) hyperarousal—e.g. sleep disturbance, irritability.

Management—debriefing in the early stages is not recommended as a routine intervention for all who have been exposed to traumatic events. However, PTSD is a disabling condition that is often comorbid with other psychiatric problems. Trauma-focused psychological interventions are the treatment of choice, with pharmacological interventions being a second-line treatment for those who do not wish to engage in a psychological intervention.

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