Structure and function of skin
- DOI:
- 10.1093/med/9780199204854.003.2301_update_001
Skin provides a mechanical barrier against the external environment, but has further roles in thermoregulation, metabolism, and the regulation of fluid balance, as well as being socially important in contributing to physical and chemical attraction between individuals.
There are more than 1000 different skin diseases, although relatively few are commonly encountered in general medical practice. However, several skin conditions can reflect a general medical problem such as a systemic infection, or a cutaneous manifestation of internal disease (e.g. patients with underlying malignancy, endocrine disorders or chronic inflammatory diseases). An understanding of skin structure and function is also important in dealing with the common clinical scenario of ‘skin failure’ resulting from adverse drug reactions, burns, or extensive trauma....
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