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Disorders of the synthesis or function of haemoglobin 

Disorders of the synthesis or function of haemoglobin

Chapter:
Disorders of the synthesis or function of haemoglobin
Author(s):

D.J. Weatherall

DOI:
10.1093/med/9780199204854.003.220507_update_003

Update:

Treatment – new recommendations for monitoring of patients receiving deferiprone and deferasirox.

Updated on 30 Jul 2015. The previous version of this content can be found here.
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date: 23 August 2017

The inherited disorders of haemoglobin are the commonest single-gene disorders in the world. They cause much morbidity and mortality in those individuals who are severely affected, and place a major burden on health services in some places, in particular the Mediterranean region, sub-Saharan Africa, and South-East Asia, when economic conditions improve and infant and childhood death rates fall. Mass migrations of populations from high-incidence areas for the haemoglobin disorders, together with the general ease of international travel, means that these conditions are being seen with increasing frequency in parts of the world where they have not been recognized previously....

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