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Membranous nephropathy 

Membranous nephropathy

Chapter:
Membranous nephropathy
Author(s):

Dwomoa Adu

DOI:
10.1093/med/9780199204854.003.210804

May 25, 2011: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

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date: 27 June 2017

Membranous nephropathy, which accounts for 20 to 30% of cases of the nephrotic syndrome in adults, is defined histologically by the presence of subepithelial immune deposits on the outer surface of the glomerular basement membrane. The immune mechanisms that lead to this are uncertain, and most cases are of unknown cause (idiopathic), but the condition can be associated with autoimmune diseases (systemic lupus erythematosus), malignancy (in 10% of cases, most commonly lung and prostate cancer), drugs, and infections....

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