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Immunoglobulin A nephropathy and Henoch–Schönlein purpura 

Immunoglobulin A nephropathy and Henoch–Schönlein purpura
Chapter:
Immunoglobulin A nephropathy and Henoch–Schönlein purpura
Author(s):

Jonathan Barratt

and John Feehally

DOI:
10.1093/med/9780199204854.003.210801_update_002

Update:

Updated information on the genetics of Immunoglobulin A nephropathy (IgAN)

New table showing RCTs examining the efficacy of a variety of novel therapies in IgAN

Updated further reading

Updated on 22 Sep 2016. The previous version of this content can be found here.
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date: 19 October 2017

Immunoglobulin A nephropathy (IgAN) is the commonest pattern of glomerulonephritis identified in areas of the world where renal biopsy is widely practised. It is defined pathologically by IgA deposition in the glomerular mesangium accompanied by a mesangial proliferative glomerulonephritis which may vary greatly in severity. Aetiology is uncertain, but abnormalities of IgA1 hinge-region ...

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