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Osteoporosis 

Osteoporosis
Chapter:
Osteoporosis
Author(s):

Juliet Compston

DOI:
10.1093/med/9780199204854.003.2004_update_002

Update:

This chapter has been thoroughly revised in December 2013, including emphasis that alendronate is the most cost-effective option in most postmenopausal women and older men.

Updated on 29 May 2014. The previous version of this content can be found here.
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date: 19 October 2017

Osteoporosis is characterized by a reduction in bone mass and disruption of bone architecture, resulting in increased bone fragility and fracture risk, with fractures of the distal radius (Colles’ fracture), spine and proximal femur being most characteristic. One in two women and one in five men over the age of 50 years will suffer an osteoporotic fracture during their remaining lifetime, with massive cost to health care services....

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