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Oxford Textbook of Medicine (5 ed.)

Edited by David A. Warrell, Timothy M. Cox, John D. Firth

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Latest update

The May 2013 update sees updates to chapters focusing on Respiratory Medicine and Haematology.

Respiratory Medicine updates include substantial updates to key chapters and new material on a wide range of topics including: new bronchoscopic techniques for early detection of lung cancer, specific causes of effusion and pleural disease, and chronic obstructive pulmonary disease.

Haematology updates include extensive revisions of key chapters on chronic myeloid leukaemia, aplastic anaemia and bone marrow failure disorders, and blood transfusion, with new information on a wide range of matters.

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Publisher:
Oxford University Press
Print Publication Date:
May 2010
Print ISBN-13:
9780199204854
Published to Oxford Medicine:
May 2010
DOI:
10.1093/med/9780199204854.001.1

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Disclaimer

Oxford University Press makes no representation, express or implied, that the drug dosages in this book are correct. Readers must therefore always check the product information and clinical procedures with the most up to date published product information and data sheets provided by the manufacturers and the most recent codes of conduct and safety regulations. The authors and the publishers do not accept responsibility or legal liability for any errors in the text or for the misuse or misapplication of material in this work. Except where otherwise stated, drug dosages and recommendations are for the non-pregnant adult who is not breastfeeding.

Contents

Lipoid (lipid) pneumonia

Chapter:
Lipoid (lipid) pneumonia
Author(s):

D.J. Hendrick

DOI:
10.1093/med/9780199204854.003.181409

May 30, 2013: This chapter has been re-evaluated and remains up-to-date. No changes have been necessary.

Lipids that accumulate within airways and alveolae are difficult to remove and may lead to an inflammatory response. Exogenous lipid can be aspirated in those with impaired swallowing mechanisms who take or are given agents such as olive oil or paraffin, or can be inhaled from oil aerosols/mists. Endogenous lipid can (rarely) be deposited when chronic inflammation accompanies some cause of localized bronchial obstruction. Presentation is with a chronic ‘pneumonic’ illness or asymptomatic radiographic abnormality, when appearances may closely simulate bronchial carcinoma. Demonstration of lipid material within pulmonary secretions or alveolar macrophages obtained from sputum or bronchoalveolar lavage is diagnostic. If treatment is needed, therapeutic bronchoalveolar lavage may remove substantial quantities of lipid from the alveoli; episodes of secondary bacterial infection require antibiotic treatment.

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