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Bronchiectasis 

Bronchiectasis

Chapter:
Bronchiectasis
Author(s):

R.D. Bilton

DOI:
10.1093/med/9780199204854.003.1809_update_001

Update:

Management—revised recommendations on treatment of patients with chronic Pseudomonas aeruginosa infection; discussion of use of azithromycin, with antimicrobial and immunomodulatory effects that can reduce exacerbations in selected patients.

Updated on 30 May 2013. The previous version of this content can be found here.
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date: 23 May 2017

Bronchiectatic lung contains permanently dilated subsegmental airways that are inflamed, tortuous, and often partially or totally obstructed with secretions. It arises as a result of the combination of an infectious insult with associated impaired clearance mechanisms: local obstruction and infection distal to the obstruction are both required. Causes include developmental defects, immune deficiency, mucociliary clearance defects and mechanical obstruction, but in many cases (40–60%) the cause is unknown....

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