Show Summary Details
Page of

Takayasu’s arteritis 

Takayasu’s arteritis
Chapter:
Takayasu’s arteritis
Author(s):

Yasushi Kobayashi

DOI:
10.1093/med/9780199204854.003.161404_update_003

Update:

Classification – revised. Management – use of anti-TNF-? therapy and anti-IL-6 receptor therapy in refractory cases.

Updated on 29 Oct 2015. The previous version of this content can be found here.
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2015. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy).

date: 21 September 2017

Takayasu’s arteritis is a chronic granulomatous vasculitis of unknown cause characterized by stenosis, occlusion, and aneurysm of large elastic arteries, mainly the aorta and its branches. It mainly affects young women, predominantly in Asian, Middle Eastern, and South American countries.

Clinical presentation—symptoms in the acute stage are nonspecific, such as general fatigue and fever, which can persist for months to years. Symptoms in the chronic stage depend on the anatomical location of the vascular lesions, with typical complaints relating to ischaemia of the brain, eyes, or arms. The commonest finding on physical examination is a weak or absent pulse in one or both brachial, radial, and/or ulnar arteries. Bruits can often be heard over affected arteries. Hypertension and aortic insufficiency are strongly associated with poor prognosis....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.