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Management of acute coronary syndrome 

Management of acute coronary syndrome

Chapter:
Management of acute coronary syndrome
Author(s):

Keith A.A. Fox

and Rajesh K. Kharbanda

DOI:
10.1093/med/9780199204854.003.161305_update_003

Update:

Role of anti-Xa inhibitors (Fondaparinux) and bivalirudin in ACS management. This chapter now includes content from retired Chapter 16.13.8.

Updated on 29 Oct 2015. The previous version of this content can be found here.
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date: 23 August 2017

The acute coronary syndrome (ACS) is precipitated by an abrupt change in an atheromatous plaque, resulting in increased obstruction to perfusion and ischaemia or infarction in the territory supplied by the affected vessel. The clinical consequences of plaque rupture can range from an entirely silent episode, through to unstable symptoms of ischaemia without infarction, to profound ischaemia complicated by progressive infarction, heart failure, and risk of sudden death. Clinical presentation with an ACS identifies a patient at high risk of further cardiovascular events requiring a defined acute and long-term management strategy....

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