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Cardiac transplantation and mechanical circulatory support 

Cardiac transplantation and mechanical circulatory support

Chapter:
Cardiac transplantation and mechanical circulatory support
Author(s):

Jayan Parameshwar

and Steven Tsui

DOI:
10.1093/med/9780199204854.003.160502_update_002

Update:

Indications and use of ventricular assist devices.

Updated on 29 Oct 2015. The previous version of this content can be found here.
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date: 22 August 2017

Cardiac transplantation is the treatment of choice for selected patients with advanced heart failure: median survival exceeds 10 years and recipients enjoy an excellent quality of life, but availability is severely limited by shortage of donor organs. The need for lifelong immunosuppression is associated with side effects, including an increased incidence of malignancy. Newer immunosuppressive agents offer promise in reducing nephrotoxicity of conventional regimens and in delaying the onset of (currently inevitable) cardiac allograft vasculopathy....

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