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Autoimmune hepatitis 

Autoimmune hepatitis

Chapter:
Autoimmune hepatitis
Author(s):

H.J.F. Hodgson

DOI:
10.1093/med/9780199204854.003.152102_update_001

Update:

Chapter reviewed, minor updates made, further reading updated.

A relevant case history from Oxford Case Histories in Gastroenterology and Hepatology has been added to this chapter.

Updated on 28 Nov 2012. The previous version of this content can be found here.
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date: 26 May 2017

Case History—A 24 yr old woman presenting with a short history of jaundice.

Autoimmune hepatitis describes chronic inflammation in the liver attributed to immune responses against self-antigens in the liver, typically in the form of a marked portal tract infiltrate containing both plasma cells and T cells. It usually affects women (female:male, 8:1), is often familial, and 60% of patients have other autoimmune diseases (e.g. thyroiditis, type 1 diabetes) in addition....

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