Show Summary Details
Page of

Immune disorders of the gastrointestinal tract 

Immune disorders of the gastrointestinal tract

Chapter:
Immune disorders of the gastrointestinal tract
Author(s):

D.J. Unsworth

DOI:
10.1093/med/9780199204854.003.1505_update_001

Update:

Autoimmunity and the gastrointestinal tract—description of a rare monogenic autoimmune condition, IPEX 1 (immunodysregulation, polyendocrinopathy, enteropathy).

Coeliac disease—expanded discussion of genetic background and pathogenesis.

Skin prick tests—discussion of use of serum-based assays to determine optimal timing.

Antibody tests—comment on allergen component specific IgE antibody tests, which may have enhanced specificity, and a cautionary note regarding other non-IgE tests that must be interpreted with extreme caution.

Updated on 28 Nov 2012. The previous version of this content can be found here.
Page of

PRINTED FROM OXFORD MEDICINE ONLINE (www.oxfordmedicine.com). © Oxford University Press, 2015. All Rights Reserved. Under the terms of the licence agreement, an individual user may print out a PDF of a single chapter of a title in Oxford Medicine Online for personal use (for details see Privacy Policy).

date: 26 June 2017

The gastrointestinal tract is protected by gut-associated lymphoid tissue that provides an environment where interaction occurs between luminal antigen and specially adapted immune tissue in Peyer’s patches (small intestine only) or lymphoid follicles. T and B lymphocytes primed in the gut migrate into the systemic circulation via the thoracic duct but home preferentially to the lamina propria of the intestine. Plasma cells of the lamina propria secrete immunoglobulin A as a dimer linked by a joining peptide....

Access to the complete content on Oxford Medicine Online requires a subscription or purchase. Public users are able to search the site and view the abstracts for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.