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Disorders of the adrenal cortex 

Disorders of the adrenal cortex

Chapter:
Disorders of the adrenal cortex
Author(s):

P.M. Stewart

DOI:
10.1093/med/9780199204854.003.130701_update_001

Update:

Diagnosis of Cushing’s syndrome and primary aldosteronism—minor alterations as recommended by recent Endocrine Society guidelines.

Updated on 30 Nov 2011. The previous version of this content can be found here.
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date: 23 July 2017

Three classes of steroid hormone are produced by the adrenal cortex after uptake of precursor cholesterol from the plasma: (1) mineralocorticoids—aldosterone, deoxycorticosterone; secreted in low amounts (100–150 µg aldosterone/day) from the zona glomerulosa, mainly under the control of angiotensin II; enhance uptake of sodium principally in the colon and kidney tubule by binding to receptors whose specificity for mineralocorticoids is established in these tissues by expression of 11 ...

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